Valcarce C - Search Results

1

The SimpliciT1 Study: A Randomized, Double-Blind, Placebo-Controlled Phase 1b/2 Adaptive Study of TTP399, a Hepatoselective Glucokinase Activator, for Adjunctive Treatment of Type 1 Diabetes.

Klein KR, Freeman JLR, Dunn I, Dvergsten C, Kirkman MS, Buse JB, Valcarce C; SimpliciT1 research group. Klein KR, et al. Among authors: valcarce c. Diabetes Care. 2021 Apr;44(4):960-968. doi: 10.2337/dc20-2684. Epub 2021 Feb 23. Diabetes Care. 2021. PMID: 33622669 Free PMC article. Clinical Trial.

2

Targeting hepatic glucokinase to treat diabetes with TTP399, a hepatoselective glucokinase activator.

Vella A, Freeman JLR, Dunn I, Keller K, Buse JB, Valcarce C. Vella A, et al. Among authors: valcarce c. Sci Transl Med. 2019 Jan 16;11(475):eaau3441. doi: 10.1126/scitranslmed.aau3441. Sci Transl Med. 2019. PMID: 30651321 Clinical Trial.

3

Impact of the hepatoselective glucokinase activator TTP399 on ketoacidosis during insulin withdrawal in people with type 1 diabetes.

Klein KR, Boeder SC, Freeman JLR, Dunn I, Dvergsten C, Madduri S, Giovannetti ER, Valcarce C, Buse JB, Pettus JH. Klein KR, et al. Among authors: valcarce c. Diabetes Obes Metab. 2022 Aug;24(8):1439-1447. doi: 10.1111/dom.14697. Epub 2022 Jun 4. Diabetes Obes Metab. 2022. PMID: 35661378 Free PMC article. Clinical Trial.

4

Development of Azeliragon, an Oral Small Molecule Antagonist of the Receptor for Advanced Glycation Endproducts, for the Potential Slowing of Loss of Cognition in Mild Alzheimer's Disease.

Burstein AH, Sabbagh M, Andrews R, Valcarce C, Dunn I, Altstiel L. Burstein AH, et al. Among authors: valcarce c. J Prev Alzheimers Dis. 2018;5(2):149-154. doi: 10.14283/jpad.2018.18. J Prev Alzheimers Dis. 2018. PMID: 29616709 Review.

5

Effects of AgRP inhibition on energy balance and metabolism in rodent models.

Dutia R, Kim AJ, Modes M, Rothlein R, Shen JM, Tian YE, Ihbais J, Victory SF, Valcarce C, Wardlaw SL. Dutia R, et al. Among authors: valcarce c. PLoS One. 2013 Jun 6;8(6):e65317. doi: 10.1371/journal.pone.0065317. Print 2013. PLoS One. 2013. PMID: 23762342 Free PMC article.

6

The epidermal growth factor precursor. A calcium-binding, beta-hydroxyasparagine containing modular protein present on the surface of platelets.

Valcarce C, Björk I, Stenflo J. Valcarce C, et al. Eur J Biochem. 1999 Feb;260(1):200-7. doi: 10.1046/j.1432-1327.1999.00156.x. Eur J Biochem. 1999. PMID: 10091600 Free article.

7

Mammalian adaptation to extrauterine environment: mitochondrial functional impairment caused by prematurity.

Valcarce C, Izquierdo JM, Chamorro M, Cuezva JM. Valcarce C, et al. Biochem J. 1994 Nov 1;303 ( Pt 3)(Pt 3):855-62. doi: 10.1042/bj3030855. Biochem J. 1994. PMID: 7980455 Free PMC article.

8

Calcium-dependent interaction between gamma-carboxyglutamic acid-containing and N-terminal epidermal growth factor-like modules in factor X.

Valcarce C, Holmgren A, Stenflo J. Valcarce C, et al. J Biol Chem. 1994 Oct 21;269(42):26011-6. J Biol Chem. 1994. PMID: 7929311 Free article.

9

Calcium affinity of the NH2-terminal epidermal growth factor-like module of factor X. Effect of the gamma-carboxyglutamic acid-containing module.

Valcarce C, Selander-Sunnerhagen M, Tämlitz AM, Drakenberg T, Björk I, Stenflo J. Valcarce C, et al. J Biol Chem. 1993 Dec 15;268(35):26673-8. J Biol Chem. 1993. PMID: 8253800 Free article.

10

Isolation of intact modules from noncatalytic parts of vitamin K-dependent coagulation factors IX and X and protein C.

Valcarce C, Persson E, Astermark J, Ohlin AK, Stenflo J. Valcarce C, et al. Methods Enzymol. 1993;222:416-35. doi: 10.1016/0076-6879(93)22027-d. Methods Enzymol. 1993. PMID: 8412808 No abstract available.

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