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A weakened interface in the P182L variant of HSP27 associated with severe Charcot-Marie-Tooth neuropathy causes aberrant binding to interacting proteins.
Alderson TR, Adriaenssens E, Asselbergh B, Pritišanac I, Van Lent J, Gastall HY, Wälti MA, Louis JM, Timmerman V, Baldwin AJ, Lp Benesch J. Alderson TR, et al. Among authors: pritisanac i. EMBO J. 2021 Apr 15;40(8):e103811. doi: 10.15252/embj.2019103811. Epub 2021 Mar 1. EMBO J. 2021. PMID: 33644875 Free PMC article.
Local unfolding of the HSP27 monomer regulates chaperone activity.
Alderson TR, Roche J, Gastall HY, Dias DM, Pritišanac I, Ying J, Bax A, Benesch JLP, Baldwin AJ. Alderson TR, et al. Among authors: pritisanac i. Nat Commun. 2019 Mar 6;10(1):1068. doi: 10.1038/s41467-019-08557-8. Nat Commun. 2019. PMID: 30842409 Free PMC article.
Automated assignment of methyl NMR spectra from large proteins.
Pritišanac I, Alderson TR, Güntert P. Pritišanac I, et al. Prog Nucl Magn Reson Spectrosc. 2020 Jun-Aug;118-119:54-73. doi: 10.1016/j.pnmrs.2020.04.001. Epub 2020 Apr 24. Prog Nucl Magn Reson Spectrosc. 2020. PMID: 32883449 Free article. Review.
FOXO transcription factors differ in their dynamics and intra/intermolecular interactions.
Spreitzer E, Alderson TR, Bourgeois B, Eggenreich L, Habacher H, Brahmersdorfer G, Pritišanac I, Sánchez-Murcia PA, Madl T. Spreitzer E, et al. Among authors: pritisanac i. Curr Res Struct Biol. 2022 Apr 27;4:118-133. doi: 10.1016/j.crstbi.2022.04.001. eCollection 2022. Curr Res Struct Biol. 2022. PMID: 35573459 Free PMC article.
21 results