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A Phase II, Single-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Therapeutic Efficacy of Intranasal Glulisine in Amnestic Mild Cognitive Impairment and Probable Mild Alzheimer's Disease.
Rosenbloom M, Barclay TR, Kashyap B, Hage L, O'Keefe LR, Svitak A, Pyle M, Frey W, Hanson LR. Rosenbloom M, et al. Among authors: svitak a. Drugs Aging. 2021 May;38(5):407-415. doi: 10.1007/s40266-021-00845-7. Epub 2021 Mar 15. Drugs Aging. 2021. PMID: 33719017 Clinical Trial.
Inactivation of the human brain muscarinic acetylcholine receptor by oxidative damage catalyzed by a low molecular weight endogenous inhibitor from Alzheimer's brain is prevented by pyrophosphate analogs, bioflavonoids and other antioxidants.
Fawcett JR, Bordayo EZ, Jackson K, Liu H, Peterson J, Svitak A, Frey WH 2nd. Fawcett JR, et al. Among authors: svitak a. Brain Res. 2002 Sep 20;950(1-2):10-20. doi: 10.1016/s0006-8993(02)02981-5. Brain Res. 2002. PMID: 12231224
Intranasal delivery of insulin via the olfactory nerve pathway.
Renner DB, Svitak AL, Gallus NJ, Ericson ME, Frey WH 2nd, Hanson LR. Renner DB, et al. Among authors: svitak al. J Pharm Pharmacol. 2012 Dec;64(12):1709-14. doi: 10.1111/j.2042-7158.2012.01555.x. Epub 2012 Jul 4. J Pharm Pharmacol. 2012. PMID: 23146033
Intranasal Coadministration of a Diazepam Prodrug with a Converting Enzyme Results in Rapid Absorption of Diazepam in Rats.
Rautiola D, Maglalang PD, Cheryala N, Nelson KM, Georg GI, Fine JM, Svitak AL, Faltesek KA, Hanson LR, Mishra U, Coles LD, Cloyd JC, Siegel RA. Rautiola D, et al. Among authors: svitak al. J Pharmacol Exp Ther. 2019 Sep;370(3):796-805. doi: 10.1124/jpet.118.255943. Epub 2019 Mar 5. J Pharmacol Exp Ther. 2019. PMID: 30837282 Free PMC article.
14 results