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Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's disease.
Walgrave H, Balusu S, Snoeck S, Vanden Eynden E, Craessaerts K, Thrupp N, Wolfs L, Horré K, Fourne Y, Ronisz A, Silajdžić E, Penning A, Tosoni G, Callaerts-Vegh Z, D'Hooge R, Thal DR, Zetterberg H, Thuret S, Fiers M, Frigerio CS, De Strooper B, Salta E. Walgrave H, et al. Among authors: horre k. Cell Stem Cell. 2021 Oct 7;28(10):1805-1821.e8. doi: 10.1016/j.stem.2021.05.001. Epub 2021 May 24. Cell Stem Cell. 2021. PMID: 34033742 Free article.
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression.
Hébert SS, Horré K, Nicolaï L, Papadopoulou AS, Mandemakers W, Silahtaroglu AN, Kauppinen S, Delacourte A, De Strooper B. Hébert SS, et al. Among authors: horre k. Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6415-20. doi: 10.1073/pnas.0710263105. Epub 2008 Apr 23. Proc Natl Acad Sci U S A. 2008. PMID: 18434550 Free PMC article.
MicroRNA regulation of Alzheimer's Amyloid precursor protein expression.
Hébert SS, Horré K, Nicolaï L, Bergmans B, Papadopoulou AS, Delacourte A, De Strooper B. Hébert SS, et al. Among authors: horre k. Neurobiol Dis. 2009 Mar;33(3):422-8. doi: 10.1016/j.nbd.2008.11.009. Epub 2008 Dec 9. Neurobiol Dis. 2009. PMID: 19110058
gamma-Secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease.
Serneels L, Van Biervliet J, Craessaerts K, Dejaegere T, Horré K, Van Houtvin T, Esselmann H, Paul S, Schäfer MK, Berezovska O, Hyman BT, Sprangers B, Sciot R, Moons L, Jucker M, Yang Z, May PC, Karran E, Wiltfang J, D'Hooge R, De Strooper B. Serneels L, et al. Among authors: horre k. Science. 2009 May 1;324(5927):639-42. doi: 10.1126/science.1171176. Epub 2009 Mar 19. Science. 2009. PMID: 19299585 Free PMC article.
Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer's disease mouse models.
Huang Y, Skwarek-Maruszewska A, Horré K, Vandewyer E, Wolfs L, Snellinx A, Saito T, Radaelli E, Corthout N, Colombelli J, Lo AC, Van Aerschot L, Callaerts-Vegh Z, Trabzuni D, Bossers K, Verhaagen J, Ryten M, Munck S, D'Hooge R, Swaab DF, Hardy J, Saido TC, De Strooper B, Thathiah A. Huang Y, et al. Among authors: horre k. Sci Transl Med. 2015 Oct 14;7(309):309ra164. doi: 10.1126/scitranslmed.aab3492. Sci Transl Med. 2015. PMID: 26468326
PLD3 gene and processing of APP.
Fazzari P, Horre K, Arranz AM, Frigerio CS, Saito T, Saido TC, De Strooper B. Fazzari P, et al. Among authors: horre k. Nature. 2017 Jan 25;541(7638):E1-E2. doi: 10.1038/nature21030. Nature. 2017. PMID: 28128235 No abstract available.
Alzheimer's-Causing Mutations Shift Aβ Length by Destabilizing γ-Secretase-Aβn Interactions.
Szaruga M, Munteanu B, Lismont S, Veugelen S, Horré K, Mercken M, Saido TC, Ryan NS, De Vos T, Savvides SN, Gallardo R, Schymkowitz J, Rousseau F, Fox NC, Hopf C, De Strooper B, Chávez-Gutiérrez L. Szaruga M, et al. Among authors: horre k. Cell. 2017 Jul 27;170(3):443-456.e14. doi: 10.1016/j.cell.2017.07.004. Cell. 2017. PMID: 28753424 Free article.
Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation.
Sachse SM, Lievens S, Ribeiro LF, Dascenco D, Masschaele D, Horré K, Misbaer A, Vanderroost N, De Smet AS, Salta E, Erfurth ML, Kise Y, Nebel S, Van Delm W, Plaisance S, Tavernier J, De Strooper B, De Wit J, Schmucker D. Sachse SM, et al. Among authors: horre k. EMBO J. 2019 Mar 15;38(6):e99669. doi: 10.15252/embj.201899669. Epub 2019 Feb 11. EMBO J. 2019. PMID: 30745319 Free PMC article.
25 results