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Airway administration of OM-85, a bacterial lysate, blocks experimental asthma by targeting dendritic cells and the epithelium/IL-33/ILC2 axis.
Pivniouk V, Gimenes-Junior JA, Ezeh P, Michael A, Pivniouk O, Hahn S, VanLinden SR, Malone SP, Abidov A, Anderson D, Gozdz J, DeVries A, Martinez FD, Pasquali C, Vercelli D. Pivniouk V, et al. J Allergy Clin Immunol. 2022 Mar;149(3):943-956. doi: 10.1016/j.jaci.2021.09.013. Epub 2021 Sep 22. J Allergy Clin Immunol. 2022. PMID: 34560105 Free PMC article.
The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression.
Pivniouk V, Pivniouk O, DeVries A, Uhrlaub JL, Michael A, Pivniouk D, VanLinden SR, Conway MY, Hahn S, Malone SP, Ezeh P, Churko JM, Anderson D, Kraft M, Nikolich-Zugich J, Vercelli D. Pivniouk V, et al. J Allergy Clin Immunol. 2022 Mar;149(3):923-933.e6. doi: 10.1016/j.jaci.2021.11.019. Epub 2021 Dec 10. J Allergy Clin Immunol. 2022. PMID: 34902435 Free PMC article.
Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children.
Stein MM, Hrusch CL, Gozdz J, Igartua C, Pivniouk V, Murray SE, Ledford JG, Marques Dos Santos M, Anderson RL, Metwali N, Neilson JW, Maier RM, Gilbert JA, Holbreich M, Thorne PS, Martinez FD, von Mutius E, Vercelli D, Ober C, Sperling AI. Stein MM, et al. Among authors: pivniouk v. N Engl J Med. 2016 Aug 4;375(5):411-421. doi: 10.1056/NEJMoa1508749. N Engl J Med. 2016. PMID: 27518660 Free PMC article.
Differential role of SLP-76 domains in T cell development and function.
Kumar L, Pivniouk V, de la Fuente MA, Laouini D, Geha RS. Kumar L, et al. Among authors: pivniouk v. Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):884-9. doi: 10.1073/pnas.022619199. Epub 2002 Jan 15. Proc Natl Acad Sci U S A. 2002. PMID: 11792851 Free PMC article.
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