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Inhibition of CBP synergizes with the RNA-dependent mechanisms of Azacitidine by limiting protein synthesis.
Diesch J, Le Pannérer MM, Winkler R, Casquero R, Muhar M, van der Garde M, Maher M, Herráez CM, Bech-Serra JJ, Fellner M, Rathert P, Brooks N, Zamora L, Gentilella A, de la Torre C, Zuber J, Götze KS, Buschbeck M. Diesch J, et al. Among authors: maher m. Nat Commun. 2021 Oct 18;12(1):6060. doi: 10.1038/s41467-021-26258-z. Nat Commun. 2021. PMID: 34663789 Free PMC article.
pH-Insensitive FRET voltage dyes.
Maher MP, Wu NT, Ao H. Maher MP, et al. J Biomol Screen. 2007 Aug;12(5):656-67. doi: 10.1177/1087057107302113. Epub 2007 May 21. J Biomol Screen. 2007. PMID: 17517905
Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8.
Maher MP, Wu N, Ravula S, Ameriks MK, Savall BM, Liu C, Lord B, Wyatt RM, Matta JA, Dugovic C, Yun S, Ver Donck L, Steckler T, Wickenden AD, Carruthers NI, Lovenberg TW. Maher MP, et al. J Pharmacol Exp Ther. 2016 May;357(2):394-414. doi: 10.1124/jpet.115.231712. Epub 2016 Mar 17. J Pharmacol Exp Ther. 2016. PMID: 26989142
HCN channels as targets for drug discovery.
Maher MP, Wu NT, Guo HQ, Dubin AE, Chaplan SR, Wickenden AD. Maher MP, et al. Comb Chem High Throughput Screen. 2009 Jan;12(1):64-72. doi: 10.2174/138620709787048028. Comb Chem High Throughput Screen. 2009. PMID: 19149492 Review.
Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8.
Ravula S, Savall BM, Wu N, Lord B, Coe K, Wang K, Seierstad M, Swanson DM, Ziff J, Nguyen M, Leung P, Rynberg R, La D, Pippel DJ, Koudriakova T, Lovenberg TW, Carruthers NI, Maher MP, Ameriks MK. Ravula S, et al. Among authors: maher mp. ACS Med Chem Lett. 2018 Jul 13;9(8):821-826. doi: 10.1021/acsmedchemlett.8b00215. eCollection 2018 Aug 9. ACS Med Chem Lett. 2018. PMID: 30128074 Free PMC article.
977 results