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Small molecule allosteric inhibitors of RORγt block Th17-dependent inflammation and associated gene expression in vivo.
PLoS One. 2021 Nov 9;16(11):e0248034. doi: 10.1371/journal.pone.0248034. eCollection 2021.
PLoS One. 2021.
PMID: 34752458
Free PMC article.
Discovery of CC-90011: A Potent and Selective Reversible Inhibitor of Lysine Specific Demethylase 1 (LSD1).
Kanouni T, Severin C, Cho RW, Yuen NY, Xu J, Shi L, Lai C, Del Rosario JR, Stansfield RK, Lawton LN, Hosfield D, O'Connell S, Kreilein MM, Tavares-Greco P, Nie Z, Kaldor SW, Veal JM, Stafford JA, Chen YK.
Kanouni T, et al. Among authors: kreilein mm.
J Med Chem. 2020 Dec 10;63(23):14522-14529. doi: 10.1021/acs.jmedchem.0c00978. Epub 2020 Oct 9.
J Med Chem. 2020.
PMID: 33034194
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Diosphenol-based approach to the a-ring functionalization of advanced Taxol precursors.
Kreilein MM, Hofferberth JE, Hart AC, Paquette LA.
Kreilein MM, et al.
J Org Chem. 2006 Sep 15;71(19):7329-36. doi: 10.1021/jo061115+.
J Org Chem. 2006.
PMID: 16958527
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Oxidative cleavage of p-methoxybenzyl ethers with methyl(trifluoromethyl)dioxirane.
Paquette LA, Kreilein MM, Bedore MW, Friedrich D.
Paquette LA, et al. Among authors: kreilein mm.
Org Lett. 2005 Oct 13;7(21):4665-7. doi: 10.1021/ol051856h.
Org Lett. 2005.
PMID: 16209505
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