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RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN.
Park S, Zhao D, Hatanpaa KJ, Mickey BE, Saha D, Boothman DA, Story MD, Wong ET, Burma S, Georgescu MM, Rangnekar VM, Chauncey SS, Habib AA. Park S, et al. Among authors: burma s. Cancer Res. 2009 May 15;69(10):4107-11. doi: 10.1158/0008-5472.CAN-09-0474. Epub 2009 May 12. Cancer Res. 2009. PMID: 19435890 Free PMC article.
Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA double-strand breaks.
Camacho CV, Mukherjee B, McEllin B, Ding LH, Hu B, Habib AA, Xie XJ, Nirodi CS, Saha D, Story MD, Balajee AS, Bachoo RM, Boothman DA, Burma S. Camacho CV, et al. Among authors: burma s. Carcinogenesis. 2010 Oct;31(10):1889-96. doi: 10.1093/carcin/bgq153. Epub 2010 Jul 26. Carcinogenesis. 2010. PMID: 20663777 Free PMC article.
Cytoplasmic TRADD confers a worse prognosis in glioblastoma.
Chakraborty S, Li L, Tang H, Xie Y, Puliyappadamba VT, Raisanen J, Burma S, Boothman DA, Cochran B, Wu J, Habib AA. Chakraborty S, et al. Among authors: burma s. Neoplasia. 2013 Aug;15(8):888-97. doi: 10.1593/neo.13608. Neoplasia. 2013. PMID: 23908590 Free PMC article.
An EGFR wild type-EGFRvIII-HB-EGF feed-forward loop regulates the activation of EGFRvIII.
Li L, Chakraborty S, Yang CR, Hatanpaa KJ, Cipher DJ, Puliyappadamba VT, Rehman A, Jiwani AJ, Mickey B, Madden C, Raisanen J, Burma S, Saha D, Wang Z, Pingle SC, Kesari S, Boothman DA, Habib AA. Li L, et al. Among authors: burma s. Oncogene. 2014 Aug 14;33(33):4253-64. doi: 10.1038/onc.2013.400. Epub 2013 Sep 30. Oncogene. 2014. PMID: 24077285 Free PMC article.
EGFR wild type antagonizes EGFRvIII-mediated activation of Met in glioblastoma.
Li L, Puliyappadamba VT, Chakraborty S, Rehman A, Vemireddy V, Saha D, Souza RF, Hatanpaa KJ, Koduru P, Burma S, Boothman DA, Habib AA. Li L, et al. Among authors: burma s. Oncogene. 2015 Jan 2;34(1):129-134. doi: 10.1038/onc.2013.534. Epub 2013 Dec 23. Oncogene. 2015. PMID: 24362532 Free PMC article.
Inhibition of DNA double-strand break repair by the dual PI3K/mTOR inhibitor NVP-BEZ235 as a strategy for radiosensitization of glioblastoma.
Gil del Alcazar CR, Hardebeck MC, Mukherjee B, Tomimatsu N, Gao X, Yan J, Xie XJ, Bachoo R, Li L, Habib AA, Burma S. Gil del Alcazar CR, et al. Among authors: burma s. Clin Cancer Res. 2014 Mar 1;20(5):1235-48. doi: 10.1158/1078-0432.CCR-13-1607. Epub 2013 Dec 23. Clin Cancer Res. 2014. PMID: 24366691 Free PMC article.
92 results