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Tumor necrosis factor and its targets in the inflammatory cytokine pathway are identified as putative transcriptomic biomarkers for escitalopram response.
Powell TR, Schalkwyk LC, Heffernan AL, Breen G, Lawrence T, Price T, Farmer AE, Aitchison KJ, Craig IW, Danese A, Lewis C, McGuffin P, Uher R, Tansey KE, D'Souza UM. Powell TR, et al. Among authors: breen g. Eur Neuropsychopharmacol. 2013 Sep;23(9):1105-14. doi: 10.1016/j.euroneuro.2012.09.009. Epub 2012 Nov 9. Eur Neuropsychopharmacol. 2013. PMID: 23142150 Clinical Trial.
Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway.
Killick R, Ribe EM, Al-Shawi R, Malik B, Hooper C, Fernandes C, Dobson R, Nolan PM, Lourdusamy A, Furney S, Lin K, Breen G, Wroe R, To AW, Leroy K, Causevic M, Usardi A, Robinson M, Noble W, Williamson R, Lunnon K, Kellie S, Reynolds CH, Bazenet C, Hodges A, Brion JP, Stephenson J, Simons JP, Lovestone S. Killick R, et al. Among authors: breen g. Mol Psychiatry. 2014 Jan;19(1):88-98. doi: 10.1038/mp.2012.163. Epub 2012 Nov 20. Mol Psychiatry. 2014. PMID: 23164821 Free PMC article.
Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes.
Kiddle SJ, Steves CJ, Mehta M, Simmons A, Xu X, Newhouse S, Sattlecker M, Ashton NJ, Bazenet C, Killick R, Adnan J, Westman E, Nelson S, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Curtis C, Breen G, Williams SC, Lovestone S, Spector TD, Dobson RJ. Kiddle SJ, et al. Among authors: breen g. Transl Psychiatry. 2015 Jun 16;5(6):e584. doi: 10.1038/tp.2015.78. Transl Psychiatry. 2015. PMID: 26080319 Free PMC article.
Transcriptomics and the mechanisms of antidepressant efficacy.
Hodgson K, Tansey KE, Powell TR, Coppola G, Uher R, Zvezdana Dernovšek M, Mors O, Hauser J, Souery D, Maier W, Henigsberg N, Rietschel M, Placentino A, Aitchison KJ, Craig IW, Farmer AE, Breen G, McGuffin P, Dobson R. Hodgson K, et al. Among authors: breen g. Eur Neuropsychopharmacol. 2016 Jan;26(1):105-112. doi: 10.1016/j.euroneuro.2015.10.009. Epub 2015 Nov 12. Eur Neuropsychopharmacol. 2016. PMID: 26621261 Clinical Trial.
Separate and combined effects of genetic variants and pre-treatment whole blood gene expression on response to exposure-based cognitive behavioural therapy for anxiety disorders.
Coleman JR, Lester KJ, Roberts S, Keers R, Lee SH, De Jong S, Gaspar H, Teismann T, Wannemüller A, Schneider S, Jöhren P, Margraf J, Breen G, Eley TC. Coleman JR, et al. Among authors: breen g. World J Biol Psychiatry. 2017 Apr;18(3):215-226. doi: 10.1080/15622975.2016.1208841. Epub 2016 Aug 24. World J Biol Psychiatry. 2017. PMID: 27376411 Clinical Trial.
577 results