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Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm.
Cerrone M, Montnach J, Lin X, Zhao YT, Zhang M, Agullo-Pascual E, Leo-Macias A, Alvarado FJ, Dolgalev I, Karathanos TV, Malkani K, Van Opbergen CJM, van Bavel JJA, Yang HQ, Vasquez C, Tester D, Fowler S, Liang F, Rothenberg E, Heguy A, Morley GE, Coetzee WA, Trayanova NA, Ackerman MJ, van Veen TAB, Valdivia HH, Delmar M. Cerrone M, et al. Among authors: delmar m. Nat Commun. 2017 Jul 24;8(1):106. doi: 10.1038/s41467-017-00127-0. Nat Commun. 2017. PMID: 28740174 Free PMC article.
Disruption of Ca2+i Homeostasis and Connexin 43 Hemichannel Function in the Right Ventricle Precedes Overt Arrhythmogenic Cardiomyopathy in Plakophilin-2-Deficient Mice.
Kim JC, Pérez-Hernández M, Alvarado FJ, Maurya SR, Montnach J, Yin Y, Zhang M, Lin X, Vasquez C, Heguy A, Liang FX, Woo SH, Morley GE, Rothenberg E, Lundby A, Valdivia HH, Cerrone M, Delmar M. Kim JC, et al. Among authors: delmar m. Circulation. 2019 Sep 17;140(12):1015-1030. doi: 10.1161/CIRCULATIONAHA.119.039710. Epub 2019 Jul 18. Circulation. 2019. PMID: 31315456 Free PMC article.
Plakophilin-2 Haploinsufficiency Causes Calcium Handling Deficits and Modulates the Cardiac Response Towards Stress.
van Opbergen CJM, Noorman M, Pfenniger A, Copier JS, Vermij SH, Li Z, van der Nagel R, Zhang M, de Bakker JMT, Glass AM, Mohler PJ, Taffet SM, Vos MA, van Rijen HVM, Delmar M, van Veen TAB. van Opbergen CJM, et al. Among authors: delmar m. Int J Mol Sci. 2019 Aug 21;20(17):4076. doi: 10.3390/ijms20174076. Int J Mol Sci. 2019. PMID: 31438494 Free PMC article.
181 results