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G-protein activation by a metabotropic glutamate receptor.
Seven AB, Barros-Álvarez X, de Lapeyrière M, Papasergi-Scott MM, Robertson MJ, Zhang C, Nwokonko RM, Gao Y, Meyerowitz JG, Rocher JP, Schelshorn D, Kobilka BK, Mathiesen JM, Skiniotis G. Seven AB, et al. Among authors: barros alvarez x. Nature. 2021 Jul;595(7867):450-454. doi: 10.1038/s41586-021-03680-3. Epub 2021 Jun 30. Nature. 2021. PMID: 34194039 Free PMC article.
The tethered peptide activation mechanism of adhesion GPCRs.
Barros-Álvarez X, Nwokonko RM, Vizurraga A, Matzov D, He F, Papasergi-Scott MM, Robertson MJ, Panova O, Yardeni EH, Seven AB, Kwarcinski FE, Su H, Peroto MC, Meyerowitz JG, Shalev-Benami M, Tall GG, Skiniotis G. Barros-Álvarez X, et al. Nature. 2022 Apr;604(7907):757-762. doi: 10.1038/s41586-022-04575-7. Epub 2022 Apr 13. Nature. 2022. PMID: 35418682 Free PMC article.
Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.
Cao C, Barros-Álvarez X, Zhang S, Kim K, Dämgen MA, Panova O, Suomivuori CM, Fay JF, Zhong X, Krumm BE, Gumpper RH, Seven AB, Robertson MJ, Krogan NJ, Hüttenhain R, Nichols DE, Dror RO, Skiniotis G, Roth BL. Cao C, et al. Among authors: barros alvarez x. Neuron. 2022 Oct 5;110(19):3154-3167.e7. doi: 10.1016/j.neuron.2022.08.006. Epub 2022 Sep 9. Neuron. 2022. PMID: 36087581 Free PMC article.
Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity.
Kaplan AL, Confair DN, Kim K, Barros-Álvarez X, Rodriguiz RM, Yang Y, Kweon OS, Che T, McCorvy JD, Kamber DN, Phelan JP, Martins LC, Pogorelov VM, DiBerto JF, Slocum ST, Huang XP, Kumar JM, Robertson MJ, Panova O, Seven AB, Wetsel AQ, Wetsel WC, Irwin JJ, Skiniotis G, Shoichet BK, Roth BL, Ellman JA. Kaplan AL, et al. Among authors: barros alvarez x. Nature. 2022 Oct;610(7932):582-591. doi: 10.1038/s41586-022-05258-z. Epub 2022 Sep 28. Nature. 2022. PMID: 36171289 Free PMC article.
Glycosomal targets for anti-trypanosomatid drug discovery.
Barros-Alvarez X, Gualdrón-López M, Acosta H, Cáceres AJ, Graminha MA, Michels PA, Concepción JL, Quiñones W. Barros-Alvarez X, et al. Curr Med Chem. 2014;21(15):1679-706. doi: 10.2174/09298673113209990139. Curr Med Chem. 2014. PMID: 23834165 Review.
18 results