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311 results

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A Phase III, prospective, double-blind, randomized, placebo-controlled trial of thrombolysis in imaging-eligible, late-window patients to assess the efficacy and safety of tenecteplase (TIMELESS): Rationale and design.
Albers GW, Campbell BC, Lansberg MG, Broderick J, Butcher K, Froehler MT, Schwamm LH, Nouh AM, Liebeskind DS, Toy F, Yang M, Massaro L, Schoeffler M, Purdon B. Albers GW, et al. Among authors: butcher k. Int J Stroke. 2023 Feb;18(2):237-241. doi: 10.1177/17474930221088400. Epub 2022 Apr 1. Int J Stroke. 2023. PMID: 35262424
Expediting MRI-based proof-of-concept stroke trials using an earlier imaging end point.
Ebinger M, Christensen S, De Silva DA, Parsons MW, Levi CR, Butcher KS, Bladin CF, Barber PA, Donnan GA, Davis SM; Echoplanar Imaging Thrombolytic Evaluation Trial Investigators. Ebinger M, et al. Stroke. 2009 Apr;40(4):1353-8. doi: 10.1161/STROKEAHA.108.532622. Epub 2009 Feb 26. Stroke. 2009. PMID: 19246703 Clinical Trial.
Assessing reperfusion and recanalization as markers of clinical outcomes after intravenous thrombolysis in the echoplanar imaging thrombolytic evaluation trial (EPITHET).
De Silva DA, Fink JN, Christensen S, Ebinger M, Bladin C, Levi CR, Parsons M, Butcher K, Barber PA, Donnan GA, Davis SM; Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) Investigators. De Silva DA, et al. Among authors: butcher k. Stroke. 2009 Aug;40(8):2872-4. doi: 10.1161/STROKEAHA.108.543595. Epub 2009 May 28. Stroke. 2009. PMID: 19478228 Clinical Trial.
Postthrombolysis blood pressure elevation is associated with hemorrhagic transformation.
Butcher K, Christensen S, Parsons M, De Silva DA, Ebinger M, Levi C, Jeerakathil T, Campbell BC, Barber PA, Bladin C, Fink J, Tress B, Donnan GA, Davis SM; EPITHET Investigators. Butcher K, et al. Stroke. 2010 Jan;41(1):72-7. doi: 10.1161/STROKEAHA.109.563767. Epub 2009 Nov 19. Stroke. 2010. PMID: 19926841 Clinical Trial.
Regional very low cerebral blood volume predicts hemorrhagic transformation better than diffusion-weighted imaging volume and thresholded apparent diffusion coefficient in acute ischemic stroke.
Campbell BC, Christensen S, Butcher KS, Gordon I, Parsons MW, Desmond PM, Barber PA, Levi CR, Bladin CF, De Silva DA, Donnan GA, Davis SM; EPITHET Investigators. Campbell BC, et al. Stroke. 2010 Jan;41(1):82-8. doi: 10.1161/STROKEAHA.109.562116. Epub 2009 Dec 3. Stroke. 2010. PMID: 19959537 Clinical Trial.
The benefits of intravenous thrombolysis relate to the site of baseline arterial occlusion in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET).
De Silva DA, Brekenfeld C, Ebinger M, Christensen S, Barber PA, Butcher KS, Levi CR, Parsons MW, Bladin CF, Donnan GA, Davis SM; Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) Investigators. De Silva DA, et al. Stroke. 2010 Feb;41(2):295-9. doi: 10.1161/STROKEAHA.109.562827. Epub 2010 Jan 7. Stroke. 2010. PMID: 20056931 Clinical Trial.
Pathophysiological determinants of worse stroke outcome in atrial fibrillation.
Tu HT, Campbell BC, Christensen S, Collins M, De Silva DA, Butcher KS, Parsons MW, Desmond PM, Barber PA, Levi CR, Bladin CF, Donnan GA, Davis SM; Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) Investigators. Tu HT, et al. Cerebrovasc Dis. 2010;30(4):389-95. doi: 10.1159/000316886. Epub 2010 Aug 5. Cerebrovasc Dis. 2010. PMID: 20693794 Clinical Trial.
EPITHET: Positive Result After Reanalysis Using Baseline Diffusion-Weighted Imaging/Perfusion-Weighted Imaging Co-Registration.
Nagakane Y, Christensen S, Brekenfeld C, Ma H, Churilov L, Parsons MW, Levi CR, Butcher KS, Peeters A, Barber PA, Bladin CF, De Silva DA, Fink J, Kimber TE, Schultz DW, Muir KW, Tress BM, Desmond PM, Davis SM, Donnan GA; EPITHET Investigators. Nagakane Y, et al. Stroke. 2011 Jan;42(1):59-64. doi: 10.1161/STROKEAHA.110.580464. Epub 2010 Dec 2. Stroke. 2011. PMID: 21127303 Clinical Trial.
311 results