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Page 1
Structure-Based Evolution of G Protein-Biased μ-Opioid Receptor Agonists.
Wang H, Hetzer F, Huang W, Qu Q, Meyerowitz J, Kaindl J, Hübner H, Skiniotis G, Kobilka BK, Gmeiner P. Wang H, et al. Among authors: skiniotis g. Angew Chem Int Ed Engl. 2022 Jun 27;61(26):e202200269. doi: 10.1002/anie.202200269. Epub 2022 Apr 29. Angew Chem Int Ed Engl. 2022. PMID: 35385593 Free PMC article.
Crystal structure of the β2 adrenergic receptor-Gs protein complex.
Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah ST, Lyons JA, Caffrey M, Gellman SH, Steyaert J, Skiniotis G, Weis WI, Sunahara RK, Kobilka BK. Rasmussen SG, et al. Among authors: skiniotis g. Nature. 2011 Jul 19;477(7366):549-55. doi: 10.1038/nature10361. Nature. 2011. PMID: 21772288 Free PMC article.
Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex.
Westfield GH, Rasmussen SG, Su M, Dutta S, DeVree BT, Chung KY, Calinski D, Velez-Ruiz G, Oleskie AN, Pardon E, Chae PS, Liu T, Li S, Woods VL Jr, Steyaert J, Kobilka BK, Sunahara RK, Skiniotis G. Westfield GH, et al. Among authors: skiniotis g. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16086-91. doi: 10.1073/pnas.1113645108. Epub 2011 Sep 13. Proc Natl Acad Sci U S A. 2011. PMID: 21914848 Free PMC article.
Visualization of arrestin recruitment by a G-protein-coupled receptor.
Shukla AK, Westfield GH, Xiao K, Reis RI, Huang LY, Tripathi-Shukla P, Qian J, Li S, Blanc A, Oleskie AN, Dosey AM, Su M, Liang CR, Gu LL, Shan JM, Chen X, Hanna R, Choi M, Yao XJ, Klink BU, Kahsai AW, Sidhu SS, Koide S, Penczek PA, Kossiakoff AA, Woods VL Jr, Kobilka BK, Skiniotis G, Lefkowitz RJ. Shukla AK, et al. Among authors: skiniotis g. Nature. 2014 Aug 14;512(7513):218-222. doi: 10.1038/nature13430. Epub 2014 Jun 22. Nature. 2014. PMID: 25043026 Free PMC article.
Highly Branched Pentasaccharide-Bearing Amphiphiles for Membrane Protein Studies.
Ehsan M, Du Y, Scull NJ, Tikhonova E, Tarrasch J, Mortensen JS, Loland CJ, Skiniotis G, Guan L, Byrne B, Kobilka BK, Chae PS. Ehsan M, et al. Among authors: skiniotis g. J Am Chem Soc. 2016 Mar 23;138(11):3789-96. doi: 10.1021/jacs.5b13233. Epub 2016 Mar 11. J Am Chem Soc. 2016. PMID: 26966956 Free PMC article.
Conformationally Preorganized Diastereomeric Norbornane-Based Maltosides for Membrane Protein Study: Implications of Detergent Kink for Micellar Properties.
Das M, Du Y, Ribeiro O, Hariharan P, Mortensen JS, Patra D, Skiniotis G, Loland CJ, Guan L, Kobilka BK, Byrne B, Chae PS. Das M, et al. Among authors: skiniotis g. J Am Chem Soc. 2017 Mar 1;139(8):3072-3081. doi: 10.1021/jacs.6b11997. Epub 2017 Feb 20. J Am Chem Soc. 2017. PMID: 28218862 Free PMC article.
Structural and Functional Analysis of a β2-Adrenergic Receptor Complex with GRK5.
Komolov KE, Du Y, Duc NM, Betz RM, Rodrigues JPGLM, Leib RD, Patra D, Skiniotis G, Adams CM, Dror RO, Chung KY, Kobilka BK, Benovic JL. Komolov KE, et al. Among authors: skiniotis g. Cell. 2017 Apr 20;169(3):407-421.e16. doi: 10.1016/j.cell.2017.03.047. Cell. 2017. PMID: 28431242 Free PMC article.
Phase-plate cryo-EM structure of a class B GPCR-G-protein complex.
Liang YL, Khoshouei M, Radjainia M, Zhang Y, Glukhova A, Tarrasch J, Thal DM, Furness SGB, Christopoulos G, Coudrat T, Danev R, Baumeister W, Miller LJ, Christopoulos A, Kobilka BK, Wootten D, Skiniotis G, Sexton PM. Liang YL, et al. Among authors: skiniotis g. Nature. 2017 Jun 1;546(7656):118-123. doi: 10.1038/nature22327. Epub 2017 Apr 24. Nature. 2017. PMID: 28437792 Free PMC article.
Vitamin E-based glycoside amphiphiles for membrane protein structural studies.
Ehsan M, Du Y, Molist I, Seven AB, Hariharan P, Mortensen JS, Ghani L, Loland CJ, Skiniotis G, Guan L, Byrne B, Kobilka BK, Chae PS. Ehsan M, et al. Among authors: skiniotis g. Org Biomol Chem. 2018 Apr 4;16(14):2489-2498. doi: 10.1039/C8OB00270C. Org Biomol Chem. 2018. PMID: 29564464 Free article.
124 results