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TLR7 gain-of-function genetic variation causes human lupus.
Brown GJ, Cañete PF, Wang H, Medhavy A, Bones J, Roco JA, He Y, Qin Y, Cappello J, Ellyard JI, Bassett K, Shen Q, Burgio G, Zhang Y, Turnbull C, Meng X, Wu P, Cho E, Miosge LA, Andrews TD, Field MA, Tvorogov D, Lopez AF, Babon JJ, López CA, Gónzalez-Murillo Á, Garulo DC, Pascual V, Levy T, Mallack EJ, Calame DG, Lotze T, Lupski JR, Ding H, Ullah TR, Walters GD, Koina ME, Cook MC, Shen N, de Lucas Collantes C, Corry B, Gantier MP, Athanasopoulos V, Vinuesa CG. Brown GJ, et al. Among authors: zhang y. Nature. 2022 May;605(7909):349-356. doi: 10.1038/s41586-022-04642-z. Epub 2022 Apr 27. Nature. 2022. PMID: 35477763 Free PMC article.
A protocol to evaluate immunoglobulin deposits in mouse glomeruli.
Nambadan SB, Stanley M, Zhang Y, Athanasopoulos V, Jiang SH. Nambadan SB, et al. Among authors: zhang y. STAR Protoc. 2022 May 11;3(2):101375. doi: 10.1016/j.xpro.2022.101375. eCollection 2022 Jun 17. STAR Protoc. 2022. PMID: 35600919 Free PMC article.
De Novo PACSIN1 Gene Variant Found in Childhood Lupus and a Role for PACSIN1/TRAF4 Complex in Toll-like Receptor 7 Activation.
Xie C, Zhou H, Athanasopoulos V, Shen Q, Zhang Y, Meng X, Burgio G, Arsov T, Lungu AC, Zhang P, Qin Y, Ma J, Wu X, Jiang X, Ding H, Meng Y, Shen N, He Y, Vinuesa CG. Xie C, et al. Among authors: zhang p, zhang y. Arthritis Rheumatol. 2023 Jun;75(6):1058-1071. doi: 10.1002/art.42416. Epub 2023 Mar 30. Arthritis Rheumatol. 2023. PMID: 36622335
Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity.
Zhang Y, Morris R, Brown GJ, Lorenzo AMD, Meng X, Kershaw NJ, Kiridena P, Burgio G, Gross S, Cappello JY, Shen Q, Wang H, Turnbull C, Lea-Henry T, Stanley M, Yu Z, Ballard FD, Chuah A, Lee JC, Hatch AM, Enders A, Masters SL, Headley AP, Trnka P, Mallon D, Fletcher JT, Walters GD, Šestan M, Jelušić M, Cook MC, Athanasopoulos V, Fulcher DA, Babon JJ, Vinuesa CG, Ellyard JI. Zhang Y, et al. J Exp Med. 2024 Apr 1;221(4):e20221080. doi: 10.1084/jem.20221080. Epub 2024 Feb 28. J Exp Med. 2024. PMID: 38417019
[A multicenter study of neonatal stroke in Shenzhen, China].
Shi LX, Feng JX, Wei YF, Lu XR, Zhang YX, Yang LY, He SN, Chen PJ, Han J, Chen C, Tu HY, Yu ZB, Huang JJ, Zeng SJ, Chen WL, Liu Y, Guo YP, Mao JY, Li XD, Zhang QS, Xie ZL, Huang MY, Yan KS, Ying EY, Chen J, Wang YR, Liu YP, Song B, Liu HY, Xiao XD, Tang H, Wang YN, Cai YS, Long Q, Xu HQ, Wang HZ, Sun Q, Han F, Zhang RB, Yang CZ, Dou L, Shi HJ, Wang R, Jiang P; Shenzhen Neonatal Data. Shi LX, et al. Among authors: zhang yx. Zhongguo Dang Dai Er Ke Za Zhi. 2024 May 15;26(5):450-455. doi: 10.7499/j.issn.1008-8830.2311094. Zhongguo Dang Dai Er Ke Za Zhi. 2024. PMID: 38802903 Chinese.
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