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The balance between protective and pathogenic immune responses to pneumonia in the neonatal lung is enforced by gut microbiota.
Stevens J, Steinmeyer S, Bonfield M, Peterson L, Wang T, Gray J, Lewkowich I, Xu Y, Du Y, Guo M, Wynn JL, Zacharias W, Salomonis N, Miller L, Chougnet C, O'Connor DH, Deshmukh H. Stevens J, et al. Among authors: bonfield m. Sci Transl Med. 2022 Jun 15;14(649):eabl3981. doi: 10.1126/scitranslmed.abl3981. Epub 2022 Jun 15. Sci Transl Med. 2022. PMID: 35704600 Free PMC article.
Replication and meta-analyses nominate numerous eosinophilic esophagitis risk genes.
Kottyan LC, Trimarchi MP, Lu X, Caldwell JM, Maddox A, Parameswaran S, Lape M, D'Mello RJ, Bonfield M, Ballaban A, Mukkada V, Putnam PE, Abonia P, Ben-Baruch Morgenstern N, Eapen AA, Wen T, Weirauch MT, Rothenberg ME. Kottyan LC, et al. Among authors: bonfield m. J Allergy Clin Immunol. 2021 Jan;147(1):255-266. doi: 10.1016/j.jaci.2020.10.018. Epub 2020 Oct 23. J Allergy Clin Immunol. 2021. PMID: 33446330 Free PMC article.
Microbiota-derived inosine programs protective CD8+ T cell responses against influenza in newborns.
Stevens J, Culberson E, Kinder J, Ramiriqui A, Gray J, Bonfield M, Shao TY, Al Gharabieh F, Peterson L, Steinmeyer S, Zacharias W, Pryhuber G, Paul O, Sengupta S, Alenghat T, Way SS, Deshmukh H. Stevens J, et al. Among authors: bonfield m. bioRxiv [Preprint]. 2024 Apr 13:2024.04.09.588427. doi: 10.1101/2024.04.09.588427. bioRxiv. 2024. PMID: 38645130 Free PMC article. Preprint.