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Early life stress exacerbates obesity in adult female mice via mineralocorticoid receptor-dependent increases in adipocyte triglyceride and glycerol content.
Leachman JR, Cincinelli C, Ahmed N, Dalmasso C, Xu M, Gatineau E, Nikolajczyk BS, Yiannikouris F, Hinds TD Jr, Loria AS. Leachman JR, et al. Among authors: yiannikouris f. Life Sci. 2022 Sep 1;304:120718. doi: 10.1016/j.lfs.2022.120718. Epub 2022 Jun 15. Life Sci. 2022. PMID: 35714704 Free PMC article.
Losartan prevents the elevation of blood pressure in adipose-PRR deficient female mice while elevated circulating sPRR activates the renin-angiotensin system.
Gatineau E, Cohn DM, Poglitsch M, Loria AS, Gong M, Yiannikouris F. Gatineau E, et al. Among authors: yiannikouris f. Am J Physiol Heart Circ Physiol. 2019 Mar 1;316(3):H506-H515. doi: 10.1152/ajpheart.00473.2018. Epub 2018 Dec 14. Am J Physiol Heart Circ Physiol. 2019. PMID: 30550352 Free PMC article.
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30 results