Bernt KM - Search Results

1

Histone methyltransferase DOT1L is essential for self-renewal of germline stem cells.

Lin H, Cheng K, Kubota H, Lan Y, Riedel SS, Kakiuchi K, Sasaki K, Bernt KM, Bartolomei MS, Luo M, Wang PJ. Lin H, et al. Among authors: bernt km. Genes Dev. 2022 Jun 1;36(11-12):752-763. doi: 10.1101/gad.349550.122. Epub 2022 Jun 23. Genes Dev. 2022. PMID: 35738678 Free PMC article.

2

Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l.

Deshpande AJ, Chen L, Fazio M, Sinha AU, Bernt KM, Banka D, Dias S, Chang J, Olhava EJ, Daigle SR, Richon VM, Pollock RM, Armstrong SA. Deshpande AJ, et al. Among authors: bernt km. Blood. 2013 Mar 28;121(13):2533-41. doi: 10.1182/blood-2012-11-465120. Epub 2013 Jan 29. Blood. 2013. PMID: 23361907 Free PMC article.

3

DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions.

Ho LL, Sinha A, Verzi M, Bernt KM, Armstrong SA, Shivdasani RA. Ho LL, et al. Among authors: bernt km. Mol Cell Biol. 2013 May;33(9):1735-45. doi: 10.1128/MCB.01463-12. Epub 2013 Feb 19. Mol Cell Biol. 2013. PMID: 23428873 Free PMC article.

4

Histone profiles in cancer.

Riedel SS, Neff T, Bernt KM. Riedel SS, et al. Among authors: bernt km. Pharmacol Ther. 2015 Oct;154:87-109. doi: 10.1016/j.pharmthera.2015.07.004. Epub 2015 Jul 22. Pharmacol Ther. 2015. PMID: 26210403 Review.

5

Ezh2 Controls an Early Hematopoietic Program and Growth and Survival Signaling in Early T Cell Precursor Acute Lymphoblastic Leukemia.

Danis E, Yamauchi T, Echanique K, Zhang X, Haladyna JN, Riedel SS, Zhu N, Xie H, Orkin SH, Armstrong SA, Bernt KM, Neff T. Danis E, et al. Among authors: bernt km. Cell Rep. 2016 Mar 1;14(8):1953-65. doi: 10.1016/j.celrep.2016.01.064. Epub 2016 Feb 18. Cell Rep. 2016. PMID: 26904942 Free PMC article.

6

MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia.

Riedel SS, Haladyna JN, Bezzant M, Stevens B, Pollyea DA, Sinha AU, Armstrong SA, Wei Q, Pollock RM, Daigle SR, Jordan CT, Ernst P, Neff T, Bernt KM. Riedel SS, et al. Among authors: bernt km. J Clin Invest. 2016 Apr 1;126(4):1438-50. doi: 10.1172/JCI80825. Epub 2016 Feb 29. J Clin Invest. 2016. PMID: 26927674 Free PMC article.

7

Transient potential receptor melastatin-2 (Trpm2) does not influence murine MLL-AF9-driven AML leukemogenesis or in vitro response to chemotherapy.

Haladyna JN, Pastuer T, Riedel SS, Perraud AL, Bernt KM. Haladyna JN, et al. Among authors: bernt km. Exp Hematol. 2016 Jul;44(7):596-602.e3. doi: 10.1016/j.exphem.2016.03.006. Epub 2016 Mar 24. Exp Hematol. 2016. PMID: 27033163 Free PMC article.

8

Epigenetic regulation of protein translation in KMT2A-rearranged AML.

Lenard A, Xie HM, Pastuer T, Shank T, Libbrecht C, Kingsley M, Riedel SS, Yuan ZF, Zhu N, Neff T, Bernt KM. Lenard A, et al. Among authors: bernt km. Exp Hematol. 2020 May;85:57-69. doi: 10.1016/j.exphem.2020.04.007. Epub 2020 May 11. Exp Hematol. 2020. PMID: 32437908 Free PMC article.

9

Specific patterns of H3K79 methylation influence genetic interaction of oncogenes in AML.

Kingsley MC, Xie HM, Chen BR, Riedel SS, Pastuer T, Bollig MK, Shank T, Libbrecht C, Stabler SP, Deshpande AJ, Intlekofer AM, Bernt KM. Kingsley MC, et al. Among authors: bernt km. Blood Adv. 2020 Jul 14;4(13):3109-3122. doi: 10.1182/bloodadvances.2020001922. Blood Adv. 2020. PMID: 32634241 Free PMC article.

10

Mesenchyme-specific loss of Dot1L histone methyltransferase leads to skeletal dysplasia phenotype in mice.

Sutter PA, Karki S, Crawley I, Singh V, Bernt KM, Rowe DW, Crocker SJ, Bayarsaihan D, Guzzo RM. Sutter PA, et al. Among authors: bernt km. Bone. 2021 Jan;142:115677. doi: 10.1016/j.bone.2020.115677. Epub 2020 Oct 3. Bone. 2021. PMID: 33022452 Free PMC article.

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