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Page 1
Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis.
Caporarello N, Lee J, Pham TX, Jones DL, Guan J, Link PA, Meridew JA, Marden G, Yamashita T, Osborne CA, Bhagwate AV, Huang SK, Nicosia RF, Tschumperlin DJ, Trojanowska M, Ligresti G. Caporarello N, et al. Among authors: tschumperlin dj. Nat Commun. 2022 Jul 25;13(1):4170. doi: 10.1038/s41467-022-31890-4. Nat Commun. 2022. PMID: 35879310 Free PMC article.
Cellular senescence mediates fibrotic pulmonary disease.
Schafer MJ, White TA, Iijima K, Haak AJ, Ligresti G, Atkinson EJ, Oberg AL, Birch J, Salmonowicz H, Zhu Y, Mazula DL, Brooks RW, Fuhrmann-Stroissnigg H, Pirtskhalava T, Prakash YS, Tchkonia T, Robbins PD, Aubry MC, Passos JF, Kirkland JL, Tschumperlin DJ, Kita H, LeBrasseur NK. Schafer MJ, et al. Among authors: tschumperlin dj. Nat Commun. 2017 Feb 23;8:14532. doi: 10.1038/ncomms14532. Nat Commun. 2017. PMID: 28230051 Free PMC article.
Zinc deficiency primes the lung for ventilator-induced injury.
Boudreault F, Pinilla-Vera M, Englert JA, Kho AT, Isabelle C, Arciniegas AJ, Barragan-Bradford D, Quintana C, Amador-Munoz D, Guan J, Choi KM; MICU Registry; Sholl L, Hurwitz S, Tschumperlin DJ, Baron RM. Boudreault F, et al. Among authors: tschumperlin dj. JCI Insight. 2017 Jun 2;2(11):e86507. doi: 10.1172/jci.insight.86507. eCollection 2017 Jun 2. JCI Insight. 2017. PMID: 28570269 Free PMC article.
Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms.
Drinane MC, Yaqoob U, Yu H, Luo F, Greuter T, Arab JP, Kostallari E, Verma VK, Maiers J, De Assuncao TM, Simons M, Mukhopadhyay D, Kisseleva T, Brenner DA, Urrutia R, Lomberk G, Gao Y, Ligresti G, Tschumperlin DJ, Revzin A, Cao S, Shah VH. Drinane MC, et al. Among authors: tschumperlin dj. JCI Insight. 2017 Dec 21;2(24):e92821. doi: 10.1172/jci.insight.92821. JCI Insight. 2017. PMID: 29263300 Free PMC article.
Matrix biomechanics and dynamics in pulmonary fibrosis.
Haak AJ, Tan Q, Tschumperlin DJ. Haak AJ, et al. Among authors: tschumperlin dj. Matrix Biol. 2018 Nov;73:64-76. doi: 10.1016/j.matbio.2017.12.004. Epub 2017 Dec 21. Matrix Biol. 2018. PMID: 29274939 Free PMC article. Review.
Mechanosensing and fibrosis.
Tschumperlin DJ, Ligresti G, Hilscher MB, Shah VH. Tschumperlin DJ, et al. J Clin Invest. 2018 Jan 2;128(1):74-84. doi: 10.1172/JCI93561. Epub 2018 Jan 2. J Clin Invest. 2018. PMID: 29293092 Free PMC article. Review.
RNAi screening identifies a mechanosensitive ROCK-JAK2-STAT3 network central to myofibroblast activation.
Oh RS, Haak AJ, Smith KMJ, Ligresti G, Choi KM, Xie T, Wang S, Walters PR, Thompson MA, Freeman MR, Manlove LJ, Chu VM, Feghali-Bostwick C, Roden AC, Schymeinsky J, Pabelick CM, Prakash YS, Vassallo R, Tschumperlin DJ. Oh RS, et al. Among authors: tschumperlin dj. J Cell Sci. 2018 May 15;131(10):jcs209932. doi: 10.1242/jcs.209932. J Cell Sci. 2018. PMID: 29678906 Free PMC article.
125 results