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IL-18-induced CD83+CCR7+ NK helper cells.
Mailliard RB, Alber SM, Shen H, Watkins SC, Kirkwood JM, Herberman RB, Kalinski P. Mailliard RB, et al. Among authors: kirkwood jm. J Exp Med. 2005 Oct 3;202(7):941-53. doi: 10.1084/jem.20050128. J Exp Med. 2005. PMID: 16203865 Free PMC article.
IL-12p70 and IL-18 gene-modified dendritic cells loaded with tumor antigen-derived peptides or recombinant protein effectively stimulate specific Type-1 CD4+ T-cell responses from normal donors and melanoma patients in vitro.
Vujanovic L, Ranieri E, Gambotto A, Olson WC, Kirkwood JM, Storkus WJ. Vujanovic L, et al. Among authors: kirkwood jm. Cancer Gene Ther. 2006 Aug;13(8):798-805. doi: 10.1038/sj.cgt.7700964. Epub 2006 Apr 28. Cancer Gene Ther. 2006. PMID: 16645618
Next generation of immunotherapy for melanoma.
Kirkwood JM, Tarhini AA, Panelli MC, Moschos SJ, Zarour HM, Butterfield LH, Gogas HJ. Kirkwood JM, et al. J Clin Oncol. 2008 Jul 10;26(20):3445-55. doi: 10.1200/JCO.2007.14.6423. J Clin Oncol. 2008. PMID: 18612161 Review.
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