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Galectin-3 is elevated in CSF and is associated with Aβ deposits and tau aggregates in brain tissue in Alzheimer's disease.
Boza-Serrano A, Vrillon A, Minta K, Paulus A, Camprubí-Ferrer L, Garcia M, Andreasson U, Antonell A, Wennström M, Gouras G, Dumurgier J, Cognat E, Molina-Porcel L, Balasa M, Vitorica J, Sánchez-Valle R, Paquet C, Venero JL, Blennow K, Deierborg T. Boza-Serrano A, et al. Among authors: antonell a. Acta Neuropathol. 2022 Nov;144(5):843-859. doi: 10.1007/s00401-022-02469-6. Epub 2022 Jul 27. Acta Neuropathol. 2022. PMID: 35895141 Free PMC article.
Cognitively preserved subjects with transitional cerebrospinal fluid ß-amyloid 1-42 values have thicker cortex in Alzheimer's disease vulnerable areas.
Fortea J, Sala-Llonch R, Bartrés-Faz D, Lladó A, Solé-Padullés C, Bosch B, Antonell A, Olives J, Sanchez-Valle R, Molinuevo JL, Rami L. Fortea J, et al. Among authors: antonell a. Biol Psychiatry. 2011 Jul 15;70(2):183-90. doi: 10.1016/j.biopsych.2011.02.017. Epub 2011 Apr 23. Biol Psychiatry. 2011. PMID: 21514924
PSEN1 mutation carriers present lower cerebrospinal fluid amyoid-β42 levels than sporadic early-onset Alzheimer's disease patients but no differences in neuronal injury biomarkers.
Balasa M, Vidal-Piñeiro D, Lladó A, Antonell A, Bosch B, Castellanos F, Bargalló N, Bartres-Faz D, Molinuevo JL, Sánchez-Valle R. Balasa M, et al. Among authors: antonell a. J Alzheimers Dis. 2012;30(3):605-16. doi: 10.3233/JAD-2012-111949. J Alzheimers Dis. 2012. PMID: 22426017
154 results