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Spidroin N-terminal domain forms amyloid-like fibril based hydrogels and provides a protein immobilization platform.
Arndt T, Jaudzems K, Shilkova O, Francis J, Johansson M, Laity PR, Sahin C, Chatterjee U, Kronqvist N, Barajas-Ledesma E, Kumar R, Chen G, Strömberg R, Abelein A, Langton M, Landreh M, Barth A, Holland C, Johansson J, Rising A. Arndt T, et al. Among authors: kumar r. Nat Commun. 2022 Aug 15;13(1):4695. doi: 10.1038/s41467-022-32093-7. Nat Commun. 2022. PMID: 35970823 Free PMC article.
Benzimidazole-based fluorophores for the detection of amyloid fibrils with higher sensitivity than Thioflavin-T.
Pravin N, Kumar R, Tripathi S, Kumar P, Mohite GM, Navalkar A, Panigrahi R, Singh N, Gadhe LG, Manchanda S, Shimozawa M, Nilsson P, Johansson J, Kumar A, Maji SK, Shanmugam M. Pravin N, et al. Among authors: kumar r, kumar a, kumar p. J Neurochem. 2021 Mar;156(6):1003-1019. doi: 10.1111/jnc.15138. Epub 2020 Sep 9. J Neurochem. 2021. PMID: 32750740 Free article.
Functionalization of amyloid fibrils via the Bri2 BRICHOS domain.
Biverstål H, Kumar R, Schellhaus AK, Sarr M, Dantuma NP, Abelein A, Johansson J. Biverstål H, et al. Among authors: kumar r. Sci Rep. 2020 Dec 10;10(1):21765. doi: 10.1038/s41598-020-78732-1. Sci Rep. 2020. PMID: 33303867 Free PMC article.
Autophagy Impairment in App Knock-in Alzheimer's Model Mice.
Jiang R, Shimozawa M, Mayer J, Tambaro S, Kumar R, Abelein A, Winblad B, Bogdanovic N, Nilsson P. Jiang R, et al. Among authors: kumar r. Front Aging Neurosci. 2022 May 19;14:878303. doi: 10.3389/fnagi.2022.878303. eCollection 2022. Front Aging Neurosci. 2022. PMID: 35663567 Free PMC article.
α-Synuclein aggregation nucleates through liquid-liquid phase separation.
Ray S, Singh N, Kumar R, Patel K, Pandey S, Datta D, Mahato J, Panigrahi R, Navalkar A, Mehra S, Gadhe L, Chatterjee D, Sawner AS, Maiti S, Bhatia S, Gerez JA, Chowdhury A, Kumar A, Padinhateeri R, Riek R, Krishnamoorthy G, Maji SK. Ray S, et al. Among authors: kumar r, kumar a. Nat Chem. 2020 Aug;12(8):705-716. doi: 10.1038/s41557-020-0465-9. Epub 2020 Jun 8. Nat Chem. 2020. PMID: 32514159
p53 amyloid formation leading to its loss of function: implications in cancer pathogenesis.
Ghosh S, Salot S, Sengupta S, Navalkar A, Ghosh D, Jacob R, Das S, Kumar R, Jha NN, Sahay S, Mehra S, Mohite GM, Ghosh SK, Kombrabail M, Krishnamoorthy G, Chaudhari P, Maji SK. Ghosh S, et al. Among authors: kumar r. Cell Death Differ. 2017 Oct;24(10):1784-1798. doi: 10.1038/cdd.2017.105. Epub 2017 Jun 23. Cell Death Differ. 2017. PMID: 28644435 Free PMC article.
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