Dowling DP - Search Results

1

High-resolution structures of a siderophore-producing cyclization domain from Yersinia pestis offer a refined proposal of substrate binding.

Gnann AD, Xia Y, Soule J, Barthélemy C, Mawani JS, Musoke SN, Castellano BM, Brignole EJ, Frueh DP, Dowling DP. Gnann AD, et al. Among authors: dowling dp. J Biol Chem. 2022 Oct;298(10):102454. doi: 10.1016/j.jbc.2022.102454. Epub 2022 Sep 5. J Biol Chem. 2022. PMID: 36063993 Free PMC article.

2

Structure and function of the two-component flavin-dependent methanesulfinate monooxygenase within bacterial sulfur assimilation.

Soule J, Gnann AD, Gonzalez R, Parker MJ, McKenna KC, Nguyen SV, Phan NT, Wicht DK, Dowling DP. Soule J, et al. Among authors: dowling dp. Biochem Biophys Res Commun. 2020 Jan 29;522(1):107-112. doi: 10.1016/j.bbrc.2019.11.008. Epub 2019 Nov 18. Biochem Biophys Res Commun. 2020. PMID: 31753487

3

Global protein dynamics as communication sensors in peptide synthetase domains.

Mishra SH, Kancherla AK, Marincin KA, Bouvignies G, Nerli S, Sgourakis N, Dowling DP, Frueh DP. Mishra SH, et al. Among authors: dowling dp. Sci Adv. 2022 Jul 15;8(28):eabn6549. doi: 10.1126/sciadv.abn6549. Epub 2022 Jul 15. Sci Adv. 2022. PMID: 35857508 Free PMC article.

4

[No title available]

[No authors listed] [No authors listed] PMID: 35552339

5

Structures of the alkanesulfonate monooxygenase MsuD provide insight into C-S bond cleavage, substrate scope, and an unexpected role for the tetramer.

Liew JJM, El Saudi IM, Nguyen SV, Wicht DK, Dowling DP. Liew JJM, et al. Among authors: dowling dp. J Biol Chem. 2021 Jul;297(1):100823. doi: 10.1016/j.jbc.2021.100823. Epub 2021 May 23. J Biol Chem. 2021. PMID: 34029591 Free PMC article.

6

Structural elements of an NRPS cyclization domain and its intermodule docking domain.

Dowling DP, Kung Y, Croft AK, Taghizadeh K, Kelly WL, Walsh CT, Drennan CL. Dowling DP, et al. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12432-12437. doi: 10.1073/pnas.1608615113. Epub 2016 Oct 17. Proc Natl Acad Sci U S A. 2016. PMID: 27791103 Free PMC article.

7

Pathways of thymidine hypermodification.

Lee YJ, Dai N, Müller SI, Guan C, Parker MJ, Fraser ME, Walsh SE, Sridar J, Mulholland A, Nayak K, Sun Z, Lin YC, Comb DG, Marks K, Gonzalez R, Dowling DP, Bandarian V, Saleh L, Corrêa IR, Weigele PR. Lee YJ, et al. Among authors: dowling dp. Nucleic Acids Res. 2022 Apr 8;50(6):3001-3017. doi: 10.1093/nar/gkab781. Nucleic Acids Res. 2022. PMID: 34522950 Free PMC article.

8

Radical use of Rossmann and TIM barrel architectures for controlling coenzyme B12 chemistry.

Dowling DP, Croft AK, Drennan CL. Dowling DP, et al. Annu Rev Biophys. 2012;41:403-27. doi: 10.1146/annurev-biophys-050511-102225. Annu Rev Biophys. 2012. PMID: 22577824 Review.

9

Structural diversity in the AdoMet radical enzyme superfamily.

Dowling DP, Vey JL, Croft AK, Drennan CL. Dowling DP, et al. Biochim Biophys Acta. 2012 Nov;1824(11):1178-95. doi: 10.1016/j.bbapap.2012.04.006. Epub 2012 Apr 28. Biochim Biophys Acta. 2012. PMID: 22579873 Free PMC article. Review.

10

Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity.

Grell TAJ, Bell BN, Nguyen C, Dowling DP, Bruender NA, Bandarian V, Drennan CL. Grell TAJ, et al. Among authors: dowling dp. Protein Sci. 2019 Jan;28(1):202-215. doi: 10.1002/pro.3529. Protein Sci. 2019. PMID: 30341796 Free PMC article.

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