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Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood.
Borcherding N, Jia W, Giwa R, Field RL, Moley JR, Kopecky BJ, Chan MM, Yang BQ, Sabio JM, Walker EC, Osorio O, Bredemeyer AL, Pietka T, Alexander-Brett J, Morley SC, Artyomov MN, Abumrad NA, Schilling J, Lavine K, Crewe C, Brestoff JR. Borcherding N, et al. Among authors: artyomov mn. Cell Metab. 2022 Oct 4;34(10):1499-1513.e8. doi: 10.1016/j.cmet.2022.08.010. Epub 2022 Sep 6. Cell Metab. 2022. PMID: 36070756 Free PMC article.
Antigen-specific B cells direct T follicular-like helper cells into lymphoid follicles to mediate Mycobacterium tuberculosis control.
Swanson RV, Gupta A, Foreman TW, Lu L, Choreno-Parra JA, Mbandi SK, Rosa BA, Akter S, Das S, Ahmed M, Garcia-Hernandez ML, Singh DK, Esaulova E, Artyomov MN, Gommerman J, Mehra S, Zuniga J, Mitreva M, Scriba TJ, Rangel-Moreno J, Kaushal D, Khader SA. Swanson RV, et al. Among authors: artyomov mn. Nat Immunol. 2023 May;24(5):855-868. doi: 10.1038/s41590-023-01476-3. Epub 2023 Apr 3. Nat Immunol. 2023. PMID: 37012543 Free PMC article.
Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages.
Huang SC, Everts B, Ivanova Y, O'Sullivan D, Nascimento M, Smith AM, Beatty W, Love-Gregory L, Lam WY, O'Neill CM, Yan C, Du H, Abumrad NA, Urban JF Jr, Artyomov MN, Pearce EL, Pearce EJ. Huang SC, et al. Among authors: artyomov mn. Nat Immunol. 2014 Sep;15(9):846-55. doi: 10.1038/ni.2956. Epub 2014 Aug 3. Nat Immunol. 2014. PMID: 25086775 Free PMC article.
Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
Lampropoulou V, Sergushichev A, Bambouskova M, Nair S, Vincent EE, Loginicheva E, Cervantes-Barragan L, Ma X, Huang SC, Griss T, Weinheimer CJ, Khader S, Randolph GJ, Pearce EJ, Jones RG, Diwan A, Diamond MS, Artyomov MN. Lampropoulou V, et al. Among authors: artyomov mn. Cell Metab. 2016 Jul 12;24(1):158-66. doi: 10.1016/j.cmet.2016.06.004. Epub 2016 Jun 30. Cell Metab. 2016. PMID: 27374498 Free PMC article.
Integrating immunometabolism and macrophage diversity.
Artyomov MN, Sergushichev A, Schilling JD. Artyomov MN, et al. Semin Immunol. 2016 Oct;28(5):417-424. doi: 10.1016/j.smim.2016.10.004. Epub 2016 Oct 19. Semin Immunol. 2016. PMID: 27771140 Free PMC article. Review.
Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression.
Williams JW, Zaitsev K, Kim KW, Ivanov S, Saunders BT, Schrank PR, Kim K, Elvington A, Kim SH, Tucker CG, Wohltmann M, Fife BT, Epelman S, Artyomov MN, Lavine KJ, Zinselmeyer BH, Choi JH, Randolph GJ. Williams JW, et al. Among authors: artyomov mn. Nat Immunol. 2020 Oct;21(10):1194-1204. doi: 10.1038/s41590-020-0768-4. Epub 2020 Sep 7. Nat Immunol. 2020. PMID: 32895539 Free PMC article.
IL-33 causes thermogenic failure in aging by expanding dysfunctional adipose ILC2.
Goldberg EL, Shchukina I, Youm YH, Ryu S, Tsusaka T, Young KC, Camell CD, Dlugos T, Artyomov MN, Dixit VD. Goldberg EL, et al. Among authors: artyomov mn. Cell Metab. 2021 Nov 2;33(11):2277-2287.e5. doi: 10.1016/j.cmet.2021.08.004. Epub 2021 Sep 1. Cell Metab. 2021. PMID: 34473956 Free PMC article.
159 results