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Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood.
Borcherding N, Jia W, Giwa R, Field RL, Moley JR, Kopecky BJ, Chan MM, Yang BQ, Sabio JM, Walker EC, Osorio O, Bredemeyer AL, Pietka T, Alexander-Brett J, Morley SC, Artyomov MN, Abumrad NA, Schilling J, Lavine K, Crewe C, Brestoff JR. Borcherding N, et al. Among authors: crewe c. Cell Metab. 2022 Oct 4;34(10):1499-1513.e8. doi: 10.1016/j.cmet.2022.08.010. Epub 2022 Sep 6. Cell Metab. 2022. PMID: 36070756 Free PMC article.
Mitochondrial metabolism is a key regulator of the fibro-inflammatory and adipogenic stromal subpopulations in white adipose tissue.
Joffin N, Paschoal VA, Gliniak CM, Crewe C, Elnwasany A, Szweda LI, Zhang Q, Hepler C, Kusminski CM, Gordillo R, Oh DY, Gupta RK, Scherer PE. Joffin N, et al. Among authors: crewe c. Cell Stem Cell. 2021 Apr 1;28(4):702-717.e8. doi: 10.1016/j.stem.2021.01.002. Epub 2021 Feb 3. Cell Stem Cell. 2021. PMID: 33539722 Free PMC article.
Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity.
Zhang Z, Funcke JB, Zi Z, Zhao S, Straub LG, Zhu Y, Zhu Q, Crewe C, An YA, Chen S, Li N, Wang MY, Ghaben AL, Lee C, Gautron L, Engelking LJ, Raj P, Deng Y, Gordillo R, Kusminski CM, Scherer PE. Zhang Z, et al. Among authors: crewe c. Cell Metab. 2021 Aug 3;33(8):1624-1639.e9. doi: 10.1016/j.cmet.2021.06.001. Epub 2021 Jun 25. Cell Metab. 2021. PMID: 34174197 Free PMC article.
Isolation of Adipose Tissue Extracellular Vesicles.
Sabio JM, Crewe C. Sabio JM, et al. Among authors: crewe c. Methods Mol Biol. 2023;2662:209-217. doi: 10.1007/978-1-0716-3167-6_19. Methods Mol Biol. 2023. PMID: 37076684
A guide to studying mitochondria transfer.
Tiash S, Brestoff JR, Crewe C. Tiash S, et al. Among authors: crewe c. Nat Cell Biol. 2023 Nov;25(11):1551-1553. doi: 10.1038/s41556-023-01246-1. Nat Cell Biol. 2023. PMID: 37853133 No abstract available.
Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis.
Zhu Y, Li N, Huang M, Bartels M, Dogné S, Zhao S, Chen X, Crewe C, Straub L, Vishvanath L, Zhang Z, Shao M, Yang Y, Gliniak CM, Gordillo R, Smith GI, Holland WL, Gupta RK, Dong B, Caron N, Xu Y, Akgul Y, Klein S, Scherer PE. Zhu Y, et al. Among authors: crewe c. Nat Commun. 2021 Aug 10;12(1):4829. doi: 10.1038/s41467-021-25025-4. Nat Commun. 2021. PMID: 34376643 Free PMC article.
32 results