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N-acylpolyamine inhibitors of HDM2 and HDMX binding to p53.
Hayashi R, Wang D, Hara T, Iera JA, Durell SR, Appella DH. Hayashi R, et al. Among authors: appella dh. Bioorg Med Chem. 2009 Dec 1;17(23):7884-93. doi: 10.1016/j.bmc.2009.10.032. Epub 2009 Oct 21. Bioorg Med Chem. 2009. PMID: 19880322 Free PMC article.
Small-molecule inactivation of HIV-1 NCp7 by repetitive intracellular acyl transfer.
Miller Jenkins LM, Ott DE, Hayashi R, Coren LV, Wang D, Xu Q, Schito ML, Inman JK, Appella DH, Appella E. Miller Jenkins LM, et al. Among authors: appella dh, appella e. Nat Chem Biol. 2010 Dec;6(12):887-9. doi: 10.1038/nchembio.456. Epub 2010 Oct 17. Nat Chem Biol. 2010. PMID: 20953192 Free PMC article.
PNA-Based Multivalent Scaffolds Activate the Dopamine D2 Receptor.
Dix AV, Conroy JL, George Rosenker KM, Sibley DR, Appella DH. Dix AV, et al. Among authors: appella dh. ACS Med Chem Lett. 2015 Mar 13;6(4):425-9. doi: 10.1021/ml500478m. eCollection 2015 Apr 9. ACS Med Chem Lett. 2015. PMID: 25893044 Free PMC article.
Preclinical evaluation of a mercaptobenzamide and its prodrug for NCp7-targeted inhibition of human immunodeficiency virus.
Hartman TL, Yang L, Helfrick AN, Hassink M, Shank NI, George Rosenker K, Scerba MT, Saha M, Hughes E, Wang AQ, Xu X, Gupta P, Buckheit RW Jr, Appella DH. Hartman TL, et al. Among authors: appella dh. Antiviral Res. 2016 Oct;134:216-225. doi: 10.1016/j.antiviral.2016.08.022. Epub 2016 Aug 26. Antiviral Res. 2016. PMID: 27568924 Free PMC article.
Probing Mercaptobenzamides as HIV Inactivators via Nucleocapsid Protein 7.
Saha M, Scerba MT, Shank NI, Hartman TL, Buchholz CA, Buckheit RW Jr, Durell SR, Appella DH. Saha M, et al. Among authors: appella dh. ChemMedChem. 2017 May 22;12(10):714-721. doi: 10.1002/cmdc.201700141. Epub 2017 Apr 25. ChemMedChem. 2017. PMID: 28395128 Free PMC article.
80 results