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Efficient recall of SARS-CoV-2 variant-reactive B cells and T responses in the elderly upon heterologous mRNA vaccines as boosters.
Rouers A, Wong N, Goh YS, Torres-Ruesta A, Tay MZ, Chang ZW, Fong SW, Neo V, Kam IKJ, Yeo NK, Huang Y, Loh CY, Hor PX, Wong JXE, Tan YJ; COVID-19 Study Group; Macary PA, Qian X, Bei W, Ngoh EZX, Salleh SNM, Wang CI, Poh XY, Rao S, Chia PY, Ong SWX, Lee TH, Lin RJH, Lim C, Teo J, Ren EC, Lye DC, Young BE, Ng LFP, Renia L. Rouers A, et al. Among authors: qian x. J Med Virol. 2023 Jan;95(1):e28258. doi: 10.1002/jmv.28258. Epub 2022 Nov 16. J Med Virol. 2023. PMID: 36305052 Free PMC article.
SARS-CoV-2 S protein:ACE2 interaction reveals novel allosteric targets.
Raghuvamsi PV, Tulsian NK, Samsudin F, Qian X, Purushotorman K, Yue G, Kozma MM, Hwa WY, Lescar J, Bond PJ, MacAry PA, Anand GS. Raghuvamsi PV, et al. Among authors: qian x. Elife. 2021 Feb 8;10:e63646. doi: 10.7554/eLife.63646. Elife. 2021. PMID: 33554856 Free PMC article.
A rapid simple point-of-care assay for the detection of SARS-CoV-2 neutralizing antibodies.
Kongsuphol P, Jia H, Cheng HL, Gu Y, Shunmuganathan BD, Chen MW, Lim SM, Ng SY, Tambyah PA, Nasir H, Gao X, Tay D, Kim S, Gupta R, Qian X, Kozma MM, Purushotorman K, McBee ME, MacAry PA, Sikes HD, Preiser PR. Kongsuphol P, et al. Among authors: qian x. Commun Med (Lond). 2021 Nov 11;1:46. doi: 10.1038/s43856-021-00045-9. eCollection 2021. Commun Med (Lond). 2021. PMID: 35602218 Free PMC article.
Analyzing COVID-19 Vaccine Responses in Transplant Recipients.
Murali TM, Shunmuganathan B, Trueman EL, Gupta R, Tan RSW, Sran HK, D'Costa MR, Wong ET, Gu Y, Cui J, Wee Kun K, Lim AQH, Qian X, Purushotorman K, Chen J, MacAry PA, Vathsala A. Murali TM, et al. Among authors: qian x. Immunohorizons. 2023 Oct 1;7(10):708-717. doi: 10.4049/immunohorizons.2300071. Immunohorizons. 2023. PMID: 37889158 Free PMC article.
Defining neutralization and allostery by antibodies against COVID-19 variants.
Tulsian NK, Palur RV, Qian X, Gu Y, D/O Shunmuganathan B, Samsudin F, Wong YH, Lin J, Purushotorman K, Kozma MM, Wang B, Lescar J, Wang CI, Gupta RK, Bond PJ, MacAry PA. Tulsian NK, et al. Among authors: qian x. Nat Commun. 2023 Nov 1;14(1):6967. doi: 10.1038/s41467-023-42408-x. Nat Commun. 2023. PMID: 37907459 Free PMC article.
Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2.
Gu Y, Shunmuganathan B, Qian X, Gupta R, Tan RSW, Kozma M, Purushotorman K, Murali TM, Tan NYJ, Preiser PR, Lescar J, Nasir H, Somani J, Tambyah PA; SCOPE Cohort Study Group; Smith KGC, Renia L, Ng LFP, Lye DC, Young BE, MacAry PA. Gu Y, et al. Among authors: qian x. Sci Rep. 2023 Dec 9;13(1):21810. doi: 10.1038/s41598-023-49231-w. Sci Rep. 2023. PMID: 38071323 Free PMC article.
Relative deficiency in interferon-γ-secreting CD4+ T cells is strongly associated with poorer COVID-19 vaccination responses in older adults.
Ho VWT, Boon LH, Cui J, Juequn Z, Shunmuganathan B, Gupta R, Tan NYJ, Qian X, Purushotorman K; SCOPE Cohort Study Group; Fong SW, Renia L, Ng LFP, Angeli V, Chen J, Kennedy BK, Ong CWM, Macary PA. Ho VWT, et al. Among authors: qian x. Aging Cell. 2024 Apr;23(4):e14099. doi: 10.1111/acel.14099. Epub 2024 Feb 5. Aging Cell. 2024. PMID: 38317404 Free PMC article.
Single-shot dendritic cell targeting SARS-CoV-2 vaccine candidate induces broad, durable and protective systemic and mucosal immunity in mice.
Cheang NYZ, Tan KS, Tan PS, Purushotorma K, Yap WC, Tullett KM, Chua BYL, Yeoh AY, Tan CQH, Qian X, Chen H, Tay DJW, Caminschi I, Tan YJ, Macary PA, Tan CW, Lahoud MH, Alonso S. Cheang NYZ, et al. Among authors: qian x. Mol Ther. 2024 May 6:S1525-0016(24)00304-6. doi: 10.1016/j.ymthe.2024.05.003. Online ahead of print. Mol Ther. 2024. PMID: 38715364 Free article.
5,601 results