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Efficient recall of SARS-CoV-2 variant-reactive B cells and T responses in the elderly upon heterologous mRNA vaccines as boosters.
J Med Virol. 2023 Jan;95(1):e28258. doi: 10.1002/jmv.28258. Epub 2022 Nov 16.
J Med Virol. 2023.
PMID: 36305052
Free PMC article.
Rapid microfluidic platform for screening and enrichment of cells secreting virus neutralizing antibodies.
Lin WN, Tay MZ, Wong JXE, Lee CY, Fong SW, Wang CI, Ng LFP, Renia L, Chen CH, Cheow LF.
Lin WN, et al. Among authors: wong jxe.
Lab Chip. 2022 Jun 28;22(13):2578-2589. doi: 10.1039/d2lc00018k.
Lab Chip. 2022.
PMID: 35694804
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Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose.
Renia L, Goh YS, Rouers A, Le Bert N, Chia WN, Chavatte JM, Fong SW, Chang ZW, Zhuo NZ, Tay MZ, Chan YH, Tan CW, Yeo NK, Amrun SN, Huang Y, Wong JXE, Hor PX, Loh CY, Wang B, Ngoh EZX, Salleh SNM, Carissimo G, Dowla S, Lim AJ, Zhang J, Lim JME, Wang CI, Ding Y, Pada S, Sun LJ, Somani J, Lee ES, Ong DLS; SCOPE Cohort Study Group; Leo YS, MacAry PA, Lin RTP, Wang LF, Ren EC, Lye DC, Bertoletti A, Young BE, Ng LFP.
Renia L, et al. Among authors: wong jxe.
Nat Commun. 2022 Aug 8;13(1):4615. doi: 10.1038/s41467-022-32312-1.
Nat Commun. 2022.
PMID: 35941158
Free PMC article.
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Heterologous booster vaccination with CoronaVac following prime vaccination with mRNA vaccine.
Goh YS, Fong SW, Rouers A, Chang ZW, Tay MZ, Chavatte JM, Zhuo NZ, Hor PX, Loh CY, Huang Y, Wong JXE, Tan YJ, Lim DRX, Wang B, Ngoh EZX, Salleh SNM, Lee RTC, Pada S, Sun LJ, Ong DLS, Somani J, Lee ES; NCID Study Group; COVID‐19 Study Group; Maurer-Stroh S, Wang CI, Leo YS, Lin RT, Ren EC, Lye DC, Young BE, Lim PL, Ng LF, Renia L.
Goh YS, et al. Among authors: wong jxe.
Clin Transl Immunology. 2022 Aug 23;11(8):e1403. doi: 10.1002/cti2.1403. eCollection 2022.
Clin Transl Immunology. 2022.
PMID: 36016852
Free PMC article.
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Waning of specific antibodies against Delta and Omicron variants five months after a third dose of BNT162b2 SARS-CoV-2 vaccine in elderly individuals.
Goh YS, Rouers A, Fong SW, Zhuo NZ, Hor PX, Loh CY, Huang Y, Neo VK, Kam IKJ, Wang B, Ngoh EZX, Salleh SNM, Lee RTC, Pada S, Sun LJ, Ong DLS, Somani J, Lee ES; NCID Study Group; COVID-19 Study Group; Maurer-Stroh S, Wang CI, Leo YS, Ren EC, Lye DC, Young BE, Ng LFP, Renia L.
Goh YS, et al.
Front Immunol. 2022 Nov 14;13:1031852. doi: 10.3389/fimmu.2022.1031852. eCollection 2022.
Front Immunol. 2022.
PMID: 36451833
Free PMC article.
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Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2.
Gu Y, Shunmuganathan B, Qian X, Gupta R, Tan RSW, Kozma M, Purushotorman K, Murali TM, Tan NYJ, Preiser PR, Lescar J, Nasir H, Somani J, Tambyah PA; SCOPE Cohort Study Group; Smith KGC, Renia L, Ng LFP, Lye DC, Young BE, MacAry PA.
Gu Y, et al.
Sci Rep. 2023 Dec 9;13(1):21810. doi: 10.1038/s41598-023-49231-w.
Sci Rep. 2023.
PMID: 38071323
Free PMC article.
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Relative deficiency in interferon-γ-secreting CD4+ T cells is strongly associated with poorer COVID-19 vaccination responses in older adults.
Ho VWT, Boon LH, Cui J, Juequn Z, Shunmuganathan B, Gupta R, Tan NYJ, Qian X, Purushotorman K; SCOPE Cohort Study Group; Fong SW, Renia L, Ng LFP, Angeli V, Chen J, Kennedy BK, Ong CWM, Macary PA.
Ho VWT, et al.
Aging Cell. 2024 Apr;23(4):e14099. doi: 10.1111/acel.14099. Epub 2024 Feb 5.
Aging Cell. 2024.
PMID: 38317404
Free PMC article.
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