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8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases.
Acta Pharm Sin B. 2023 May;13(5):2152-2175. doi: 10.1016/j.apsb.2023.01.013. Epub 2023 Jan 19.
Acta Pharm Sin B. 2023.
PMID: 37250172
Free PMC article.
Highly selective butyrylcholinesterase inhibitors related to Amaryllidaceae alkaloids - Design, synthesis, and biological evaluation.
Pidany F, Kroustkova J, Al Mamun A, Suchankova D, Brazzolotto X, Nachon F, Chantegreil F, Dolezal R, Pulkrabkova L, Muckova L, Hrabinova M, Finger V, Kufa M, Soukup O, Jun D, Jenco J, Kunes J, Novakova L, Korabecny J, Cahlikova L.
Pidany F, et al. Among authors: chantegreil f.
Eur J Med Chem. 2023 Apr 5;252:115301. doi: 10.1016/j.ejmech.2023.115301. Epub 2023 Mar 22.
Eur J Med Chem. 2023.
PMID: 36996715
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Rapid discovery and crystallography study of highly potent and selective butylcholinesterase inhibitors based on oxime-containing libraries and conformational restriction strategies.
Jing L, Wei W, Meng B, Chantegreil F, Nachon F, Martínez A, Wu G, Zhao H, Song Y, Kang D, Brazzolotto X, Zhan P, Liu X.
Jing L, et al. Among authors: chantegreil f.
Bioorg Chem. 2023 May;134:106465. doi: 10.1016/j.bioorg.2023.106465. Epub 2023 Mar 11.
Bioorg Chem. 2023.
PMID: 36933339
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Discovery of new, highly potent and selective inhibitors of BuChE - design, synthesis, in vitro and in vivo evaluation and crystallography studies.
Panek D, Pasieka A, Latacz G, Zaręba P, Szczęch M, Godyń J, Chantegreil F, Nachon F, Brazzolotto X, Skrzypczak-Wiercioch A, Walczak M, Smolik M, Sałat K, Höfner G, Wanner K, Więckowska A, Malawska B.
Panek D, et al. Among authors: chantegreil f.
Eur J Med Chem. 2023 Mar 5;249:115135. doi: 10.1016/j.ejmech.2023.115135. Epub 2023 Jan 18.
Eur J Med Chem. 2023.
PMID: 36696766
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Toxicokinetics of plasmatic VX in a swine model: comparison of a simple enzymatic titration method with a mass spectrometry method.
Fémy F, Meesemaecker G, Belverge N, Courageux C, Nervo A, Goulay R, Reymond C, Chantegreil F, Madi M, Nachon F, Taudon N, Jaffré N.
Fémy F, et al. Among authors: chantegreil f.
Arch Toxicol. 2022 Nov 3. doi: 10.1007/s00204-022-03408-w. Online ahead of print.
Arch Toxicol. 2022.
PMID: 36326899
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Discovery of multifunctional anti-Alzheimer's agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transporters.
Pasieka A, Panek D, Jończyk J, Godyń J, Szałaj N, Latacz G, Tabor J, Mezeiova E, Chantegreil F, Dias J, Knez D, Lu J, Pi R, Korabecny J, Brazzolotto X, Gobec S, Höfner G, Wanner K, Więckowska A, Malawska B.
Pasieka A, et al. Among authors: chantegreil f.
Eur J Med Chem. 2021 Jun 5;218:113397. doi: 10.1016/j.ejmech.2021.113397. Epub 2021 Mar 31.
Eur J Med Chem. 2021.
PMID: 33838585
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Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer's Disease.
Rossi M, Freschi M, de Camargo Nascente L, Salerno A, de Melo Viana Teixeira S, Nachon F, Chantegreil F, Soukup O, Prchal L, Malaguti M, Bergamini C, Bartolini M, Angeloni C, Hrelia S, Soares Romeiro LA, Bolognesi ML.
Rossi M, et al. Among authors: chantegreil f.
J Med Chem. 2021 Apr 22;64(8):4972-4990. doi: 10.1021/acs.jmedchem.1c00048. Epub 2021 Apr 8.
J Med Chem. 2021.
PMID: 33829779
Free PMC article.
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A Thermophilic Bacterial Esterase for Scavenging Nerve Agents: A Kinetic, Biophysical and Structural Study.
Bzdrenga J, Trenet E, Chantegreil F, Bernal K, Nachon F, Brazzolotto X.
Bzdrenga J, et al. Among authors: chantegreil f.
Molecules. 2021 Jan 27;26(3):657. doi: 10.3390/molecules26030657.
Molecules. 2021.
PMID: 33513869
Free PMC article.
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