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ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging.
Science. 2023 Dec 8;382(6675):eadf3208. doi: 10.1126/science.adf3208. Epub 2023 Dec 8.
Science. 2023.
PMID: 38060659
Myofibrillar myopathy hallmarks associated with ZAK deficiency.
Stonadge A, Genzor AV, Russell A, Hamed MF, Romero N, Evans G, Pownall ME, Bekker-Jensen S, Blanco G.
Stonadge A, et al. Among authors: genzor av.
Hum Mol Genet. 2023 Aug 26;32(17):2751-2770. doi: 10.1093/hmg/ddad113.
Hum Mol Genet. 2023.
PMID: 37427997
Free PMC article.
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Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response.
Snieckute G, Genzor AV, Vind AC, Ryder L, Stoneley M, Chamois S, Dreos R, Nordgaard C, Sass F, Blasius M, López AR, Brynjólfsdóttir SH, Andersen KL, Willis AE, Frankel LB, Poulsen SS, Gatfield D, Gerhart-Hines Z, Clemmensen C, Bekker-Jensen S.
Snieckute G, et al. Among authors: genzor av.
Cell Metab. 2022 Dec 6;34(12):2036-2046.e8. doi: 10.1016/j.cmet.2022.10.011. Epub 2022 Nov 15.
Cell Metab. 2022.
PMID: 36384144
Free PMC article.
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Ribosomal stress-surveillance: three pathways is a magic number.
Vind AC, Genzor AV, Bekker-Jensen S.
Vind AC, et al. Among authors: genzor av.
Nucleic Acids Res. 2020 Nov 4;48(19):10648-10661. doi: 10.1093/nar/gkaa757.
Nucleic Acids Res. 2020.
PMID: 32941609
Free PMC article.
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