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Serine-threonine phosphoregulation by PknB and Stp contributes to quiescence and antibiotic tolerance in Staphylococcus aureus.
Huemer M, Mairpady Shambat S, Hertegonne S, Bergada-Pijuan J, Chang CC, Pereira S, Gómez-Mejia A, Van Gestel L, Bär J, Vulin C, Pfammatter S, Stinear TP, Monk IR, Dworkin J, Zinkernagel AS. Huemer M, et al. Among authors: vulin c. Sci Signal. 2023 Jan 3;16(766):eabj8194. doi: 10.1126/scisignal.abj8194. Epub 2023 Jan 3. Sci Signal. 2023. PMID: 36595572
Molecular reprogramming and phenotype switching in Staphylococcus aureus lead to high antibiotic persistence and affect therapy success.
Huemer M, Mairpady Shambat S, Bergada-Pijuan J, Söderholm S, Boumasmoud M, Vulin C, Gómez-Mejia A, Antelo Varela M, Tripathi V, Götschi S, Marques Maggio E, Hasse B, Brugger SD, Bumann D, Schuepbach RA, Zinkernagel AS. Huemer M, et al. Among authors: vulin c. Proc Natl Acad Sci U S A. 2021 Feb 16;118(7):e2014920118. doi: 10.1073/pnas.2014920118. Proc Natl Acad Sci U S A. 2021. PMID: 33574060 Free PMC article.
Blunted sFasL signalling exacerbates TNF-driven neutrophil necroptosis in critically ill COVID-19 patients.
Schweizer TA, Mairpady Shambat S, Vulin C, Hoeller S, Acevedo C, Huemer M, Gomez-Mejia A, Chang CC, Baum J, Hertegonne S, Hitz E, Scheier TC, Hofmaenner DA, Buehler PK, Moch H, Schuepbach RA, Brugger SD, Zinkernagel AS. Schweizer TA, et al. Among authors: vulin c. Clin Transl Immunology. 2021 Dec 11;10(12):e1357. doi: 10.1002/cti2.1357. eCollection 2021. Clin Transl Immunology. 2021. PMID: 34938538 Free PMC article.
Hyperinflammatory environment drives dysfunctional myeloid cell effector response to bacterial challenge in COVID-19.
Mairpady Shambat S, Gómez-Mejia A, Schweizer TA, Huemer M, Chang CC, Acevedo C, Bergada-Pijuan J, Vulin C, Hofmaenner DA, Scheier TC, Hertegonne S, Parietti E, Miroshnikova N, Wendel Garcia PD, Hilty MP, Buehler PK, Schuepbach RA, Brugger SD, Zinkernagel AS. Mairpady Shambat S, et al. Among authors: vulin c. PLoS Pathog. 2022 Jan 10;18(1):e1010176. doi: 10.1371/journal.ppat.1010176. eCollection 2022 Jan. PLoS Pathog. 2022. PMID: 35007290 Free PMC article.
Quantification of within-patient Staphylococcus aureus phenotypic heterogeneity as a proxy for the presence of persisters across clinical presentations.
Bär J, Boumasmoud M, Mairpady Shambat S, Vulin C, Huemer M, Schweizer TA, Gómez-Mejia A, Eberhard N, Achermann Y, Zingg PO, Mestres CA, Brugger SD, Schuepbach RA, Kouyos RD, Hasse B, Zinkernagel AS. Bär J, et al. Among authors: vulin c. Clin Microbiol Infect. 2022 Jul;28(7):1022.e1-1022.e7. doi: 10.1016/j.cmi.2022.01.021. Epub 2022 Feb 3. Clin Microbiol Infect. 2022. PMID: 35124264 Free article.
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