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Peroxisome proliferator activated receptor-γ agonist pioglitazone improves vascular and metabolic dysfunction in systemic lupus erythematosus.
Hasni S, Temesgen-Oyelakin Y, Davis M, Chu J, Poncio E, Naqi M, Gupta S, Wang X, Oliveira C, Claybaugh D, Dey A, Lu S, Carlucci P, Purmalek M, Manna ZG, Shi Y, Ochoa-Navas I, Chen J, Mukherjee A, Han KL, Cheung F, Koroleva G, Belkaid Y, Tsang JS, Apps R, Thomas DE, Heller T, Gadina M, Playford MP, Li X, Mehta NN, Kaplan MJ. Hasni S, et al. Among authors: wang x. Ann Rheum Dis. 2022 Aug 1;81(11):1576-84. doi: 10.1136/ard-2022-222658. Online ahead of print. Ann Rheum Dis. 2022. PMID: 35914929 Free PMC article.
Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus.
Mistry P, Nakabo S, O'Neil L, Goel RR, Jiang K, Carmona-Rivera C, Gupta S, Chan DW, Carlucci PM, Wang X, Naz F, Manna Z, Dey A, Mehta NN, Hasni S, Dell'Orso S, Gutierrez-Cruz G, Sun HW, Kaplan MJ. Mistry P, et al. Among authors: wang x. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25222-25228. doi: 10.1073/pnas.1908576116. Epub 2019 Nov 21. Proc Natl Acad Sci U S A. 2019. PMID: 31754025 Free PMC article.
Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus.
Goel RR, Wang X, O'Neil LJ, Nakabo S, Hasneen K, Gupta S, Wigerblad G, Blanco LP, Kopp JB, Morasso MI, Kotenko SV, Yu ZX, Carmona-Rivera C, Kaplan MJ. Goel RR, et al. Among authors: wang x. Proc Natl Acad Sci U S A. 2020 Mar 10;117(10):5409-5419. doi: 10.1073/pnas.1916897117. Epub 2020 Feb 24. Proc Natl Acad Sci U S A. 2020. PMID: 32094169 Free PMC article.
Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism.
Gupta S, Nakabo S, Blanco LP, O'Neil LJ, Wigerblad G, Goel RR, Mistry P, Jiang K, Carmona-Rivera C, Chan DW, Wang X, Pedersen HL, Gadkari M, Howe KN, Naz F, Dell'Orso S, Hasni SA, Dempsey C, Buscetta A, Frischmeyer-Guerrerio PA, Kruszka P, Muenke M, Franco LM, Sun HW, Kaplan MJ. Gupta S, et al. Among authors: wang x. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16481-16491. doi: 10.1073/pnas.2003603117. Epub 2020 Jun 29. Proc Natl Acad Sci U S A. 2020. PMID: 32601182 Free PMC article.
Modulation of the Itaconate Pathway Attenuates Murine Lupus.
Blanco LP, Patino-Martinez E, Nakabo S, Zhang M, Pedersen HL, Wang X, Carmona-Rivera C, Claybaugh D, Yu ZX, Desta E, Kaplan MJ. Blanco LP, et al. Among authors: wang x. Arthritis Rheumatol. 2022 Dec;74(12):1971-1983. doi: 10.1002/art.42284. Epub 2022 Nov 6. Arthritis Rheumatol. 2022. PMID: 35791960
Modulation of Cardiometabolic Disease Markers by Type I Interferon Inhibition in Systemic Lupus Erythematosus.
Casey KA, Smith MA, Sinibaldi D, Seto NL, Playford MP, Wang X, Carlucci PM, Wang L, Illei G, Yu B, Wang S, Remaley AT, Mehta NN, Kaplan MJ, White WI. Casey KA, et al. Among authors: wang x, wang l, wang s. Arthritis Rheumatol. 2021 Mar;73(3):459-471. doi: 10.1002/art.41518. Epub 2021 Feb 15. Arthritis Rheumatol. 2021. PMID: 32909675 Clinical Trial.
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