Houtman JCD - Search Results

1

GRB2 dimerization mediated by SH2 domain-swapping is critical for T cell signaling and cytokine production.

Sandouk A, Xu Z, Baruah S, Tremblay M, Hopkins JB, Chakravarthy S, Gakhar L, Schnicker NJ, Houtman JCD. Sandouk A, et al. Among authors: houtman jcd. Sci Rep. 2023 Mar 2;13(1):3505. doi: 10.1038/s41598-023-30562-7. Sci Rep. 2023. PMID: 36864087 Free PMC article.

2

NetPath: a public resource of curated signal transduction pathways.

Kandasamy K, Mohan SS, Raju R, Keerthikumar S, Kumar GS, Venugopal AK, Telikicherla D, Navarro JD, Mathivanan S, Pecquet C, Gollapudi SK, Tattikota SG, Mohan S, Padhukasahasram H, Subbannayya Y, Goel R, Jacob HK, Zhong J, Sekhar R, Nanjappa V, Balakrishnan L, Subbaiah R, Ramachandra YL, Rahiman BA, Prasad TS, Lin JX, Houtman JC, Desiderio S, Renauld JC, Constantinescu SN, Ohara O, Hirano T, Kubo M, Singh S, Khatri P, Draghici S, Bader GD, Sander C, Leonard WJ, Pandey A. Kandasamy K, et al. Genome Biol. 2010 Jan 12;11(1):R3. doi: 10.1186/gb-2010-11-1-r3. Genome Biol. 2010. PMID: 20067622 Free PMC article.

3

Growth hormone-induced alteration in ErbB-2 phosphorylation status in 3T3-F442A fibroblasts.

Kim SO, Houtman JC, Jiang J, Ruppert JM, Bertics PJ, Frank SJ. Kim SO, et al. J Biol Chem. 1999 Dec 10;274(50):36015-24. doi: 10.1074/jbc.274.50.36015. J Biol Chem. 1999. PMID: 10585492 Free article.

4

Growth hormone attenuation of epidermal growth factor-induced mitogenesis.

Wiepz GJ, Houtman JC, Cha D, Bertics PJ. Wiepz GJ, et al. J Cell Physiol. 1997 Oct;173(1):44-53. doi: 10.1002/(SICI)1097-4652(199710)173:1<44::AID-JCP6>3.0.CO;2-J. J Cell Physiol. 1997. PMID: 9326448

5

Design, combinatorial chemical synthesis and in vitro characterization of novel urea based gelatinase inhibitors.

Zhang Y, Li D, Houtman JC, Witiak DT, Seltzer J, Bertics PJ, Lauhon CT. Zhang Y, et al. Bioorg Med Chem Lett. 1999 Oct 4;9(19):2823-6. doi: 10.1016/s0960-894x(99)00498-9. Bioorg Med Chem Lett. 1999. PMID: 10522699

6

Thiopurine methyltransferase pharmacogenetics. Cloning of human liver cDNA and a processed pseudogene on human chromosome 18q21.1.

Lee D, Szumlanski C, Houtman J, Honchel R, Rojas K, Overhauser J, Wieben ED, Weinshilboum RM. Lee D, et al. Drug Metab Dispos. 1995 Mar;23(3):398-405. Drug Metab Dispos. 1995. PMID: 7628307

7

Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1.

Houtman JC, Yamaguchi H, Barda-Saad M, Braiman A, Bowden B, Appella E, Schuck P, Samelson LE. Houtman JC, et al. Nat Struct Mol Biol. 2006 Sep;13(9):798-805. doi: 10.1038/nsmb1133. Epub 2006 Aug 13. Nat Struct Mol Biol. 2006. PMID: 16906159

8

PI3 kinase function is vital for the function but not formation of LAT-mediated signaling complexes.

Cruz-Orcutt N, Houtman JC. Cruz-Orcutt N, et al. Mol Immunol. 2009 Jul;46(11-12):2274-83. doi: 10.1016/j.molimm.2009.04.006. Epub 2009 May 8. Mol Immunol. 2009. PMID: 19427038

9

The T cell receptor-mediated phosphorylation of Pyk2 tyrosines 402 and 580 occurs via a distinct mechanism than other receptor systems.

Collins M, Tremblay M, Chapman N, Curtiss M, Rothman PB, Houtman JC. Collins M, et al. J Leukoc Biol. 2010 Apr;87(4):691-701. doi: 10.1189/jlb.0409227. Epub 2009 Dec 22. J Leukoc Biol. 2010. PMID: 20028775

10

The adaptor protein LAT serves as an integration node for signaling pathways that drive T cell activation.

Bartelt RR, Houtman JC. Bartelt RR, et al. Wiley Interdiscip Rev Syst Biol Med. 2013 Jan-Feb;5(1):101-10. doi: 10.1002/wsbm.1194. Epub 2012 Nov 13. Wiley Interdiscip Rev Syst Biol Med. 2013. PMID: 23150273 Free PMC article. Review.

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