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An immunometabolism subtyping system identifies S100A9+ macrophage as an immune therapeutic target in colorectal cancer based on multiomics analysis.
Bao X, Wang D, Dai X, Liu C, Zhang H, Jin Y, Tong Z, Li B, Tong C, Xin S, Li X, Wang Y, Liu L, Zhu X, Fu Q, Zheng Y, Deng J, Tian W, Guo T, Zhao P, Chen W, Fang W. Bao X, et al. Among authors: li x, li b. Cell Rep Med. 2023 Apr 18;4(4):100987. doi: 10.1016/j.xcrm.2023.100987. Epub 2023 Mar 28. Cell Rep Med. 2023. PMID: 36990096 Free PMC article.
A multiomics analysis-assisted deep learning model identifies a macrophage-oriented module as a potential therapeutic target in colorectal cancer.
Bao X, Li Q, Chen D, Dai X, Liu C, Tian W, Zhang H, Jin Y, Wang Y, Cheng J, Lai C, Ye C, Xin S, Li X, Su G, Ding Y, Xiong Y, Xie J, Tano V, Wang Y, Fu W, Deng S, Fang W, Sheng J, Ruan J, Zhao P. Bao X, et al. Among authors: li x, li q. Cell Rep Med. 2024 Feb 20;5(2):101399. doi: 10.1016/j.xcrm.2024.101399. Epub 2024 Feb 1. Cell Rep Med. 2024. PMID: 38307032 Free PMC article.
TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.
Huang D, Xu B, Liu L, Wu L, Zhu Y, Ghanbarpour A, Wang Y, Chen FJ, Lyu J, Hu Y, Kang Y, Zhou W, Wang X, Ding W, Li X, Jiang Z, Chen J, Zhang X, Zhou H, Li JZ, Guo C, Zheng W, Zhang X, Li P, Melia T, Reinisch K, Chen XW. Huang D, et al. Among authors: li jz, li x, li p. Cell Metab. 2021 Aug 3;33(8):1655-1670.e8. doi: 10.1016/j.cmet.2021.05.006. Epub 2021 May 19. Cell Metab. 2021. PMID: 34015269 Free article.
A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1.
Gallage S, Ali A, Barragan Avila JE, Seymen N, Ramadori P, Joerke V, Zizmare L, Aicher D, Gopalsamy IK, Fong W, Kosla J, Focaccia E, Li X, Yousuf S, Sijmonsma T, Rahbari M, Kommoss KS, Billeter A, Prokosch S, Rothermel U, Mueller F, Hetzer J, Heide D, Schinkel B, Machauer T, Pichler B, Malek NP, Longerich T, Roth S, Rose AJ, Schwenck J, Trautwein C, Karimi MM, Heikenwalder M. Gallage S, et al. Among authors: li x. Cell Metab. 2024 May 2:S1550-4131(24)00135-9. doi: 10.1016/j.cmet.2024.04.015. Online ahead of print. Cell Metab. 2024. PMID: 38718791 Free article.
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