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TP53 mutations identify high-risk events for peripheral T-cell lymphoma treated with CHOP-based chemotherapy.
Johnson WT, Ganesan N, Epstein-Peterson ZD, Moskowitz AJ, Stuver RN, Maccaro CR, Galasso N, Chang T, Khan N, Aypar U, Lewis NE, Zelenetz AD, Palomba ML, Matasar MJ, Noy A, Hamilton AM, Hamlin P, Caron PC, Straus DJ, Intlekofer AM, Lee Batlevi C, Kumar A, Owens CN, Sauter CS, Falchi L, Lue JK, Vardhana SA, Salles G, Dogan A, Schultz ND, Arcila ME, Horwitz SM. Johnson WT, et al. Among authors: aypar u. Blood Adv. 2023 Sep 12;7(17):5172-5186. doi: 10.1182/bloodadvances.2023009953. Blood Adv. 2023. PMID: 37078708 Free PMC article.
Clonally-Related CD5+ CLL/SLL and CD10+ high grade B-cell lymphoma suggests common neoplastic progenitor with branched disease evolution, with therapeutic implications.
Kumar P, Uppal M, Xiao W, Dogan A, Roshal M, Gao Q, Aypar U, Zhang Y, Arcila ME, Moung C, Yao J, Nafa K, Yu W, Syed MH, Park J, Kumar A, Ho C. Kumar P, et al. Among authors: aypar u. Leuk Lymphoma. 2020 Feb;61(2):460-464. doi: 10.1080/10428194.2019.1675876. Epub 2019 Oct 15. Leuk Lymphoma. 2020. PMID: 31612754 Free PMC article. No abstract available.
Myeloid/lymphoid neoplasms with eosinophilia/ basophilia and ETV6-ABL1 fusion: cell-of-origin and response to tyrosine kinase inhibition.
Yao J, Xu L, Aypar U, Meyerson HJ, Londono D, Gao Q, Baik J, Dietz J, Benayed R, Sigler A, Yabe M, Dogan A, Arcila ME, Roshal M, Zhang Y, Mauro MJ, Xiao W. Yao J, et al. Among authors: aypar u. Haematologica. 2021 Feb 1;106(2):614-618. doi: 10.3324/haematol.2020.249649. Haematologica. 2021. PMID: 32299902 Free PMC article. No abstract available.
P2RY8-CRLF2Fusion-Positive Acute Myeloid Leukemia With Myelodysplasia-Related Changes: Response to Novel Therapy.
Aypar U, Taylor J, Garcia JS, Momeni-Boroujeni A, Gao Q, Baik J, Londono D, Benayed R, Sigler A, Haddadin M, Penson AV, Arcila ME, Mullaney K, Sukhadia P, Quesada AE, Roshal M, Cullen N, Lako A, Rodig SJ, Goldberg AD, Zhang Y, Xiao W, Ho C. Aypar U, et al. JCO Precis Oncol. 2020;4:152-160. doi: 10.1200/PO.19.00294. Epub 2020 Mar 5. JCO Precis Oncol. 2020. PMID: 32395681 Free PMC article. No abstract available.
Germ cell tumors and associated hematologic malignancies evolve from a common shared precursor.
Taylor J, Donoghue MT, Ho C, Petrova-Drus K, Al-Ahmadie HA, Funt SA, Zhang Y, Aypar U, Rao P, Chavan SS, Haddadin M, Tamari R, Giralt S, Tallman MS, Rampal RK, Baez P, Kappagantula R, Kosuri S, Dogan A, Tickoo SK, Reuter VE, Bosl GJ, Iacobuzio-Donahue CA, Solit DB, Taylor BS, Feldman DR, Abdel-Wahab O. Taylor J, et al. Among authors: aypar u. J Clin Invest. 2020 Dec 1;130(12):6668-6676. doi: 10.1172/JCI139682. J Clin Invest. 2020. PMID: 32897884 Free PMC article.
Paired Tumor-Normal Sequencing Provides Insights Into the TP53-Related Cancer Spectrum in Patients With Li-Fraumeni Syndrome.
Ceyhan-Birsoy O, Selenica P, Chui MH, Jayakumaran G, Ptashkin R, Misyura M, Aypar U, Jairam S, Yang C, Li Y, Mehta N, Kemel Y, Salo-Mullen E, Maio A, Sheehan M, Zehir A, Carlo M, Latham A, Stadler Z, Robson M, Offit K, Ladanyi M, Walsh M, Reis-Filho JS, Mandelker D. Ceyhan-Birsoy O, et al. Among authors: aypar u. J Natl Cancer Inst. 2021 Nov 29;113(12):1751-1760. doi: 10.1093/jnci/djab117. J Natl Cancer Inst. 2021. PMID: 34240179 Free PMC article.
163 results