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Combinatorial inhibition of Tec kinases BTK and ITK is beneficial in ameliorating murine sclerodermatous chronic graft versus host disease.
Bone Marrow Transplant. 2023 Aug;58(8):924-935. doi: 10.1038/s41409-023-02001-8. Epub 2023 May 9.
Bone Marrow Transplant. 2023.
PMID: 37160943
Bruton's Tyrosine Kinase Inhibitors with Distinct Binding Modes Reveal Differential Functional Impact on B-Cell Receptor Signaling.
Li W, Sano R, Apatira M, DeAnda F, Gururaja T, Yang M, Lundgaard G, Pan C, Liu J, Zhai Y, Yoon WH, Wang L, Tse C, Souers AJ, Lee CH.
Li W, et al. Among authors: apatira m.
Mol Cancer Ther. 2024 Jan 3;23(1):35-46. doi: 10.1158/1535-7163.MCT-22-0642.
Mol Cancer Ther. 2024.
PMID: 37735104
Free PMC article.
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The role of PIM1 in the ibrutinib-resistant ABC subtype of diffuse large B-cell lymphoma.
Kuo HP, Ezell SA, Hsieh S, Schweighofer KJ, Cheung LW, Wu S, Apatira M, Sirisawad M, Eckert K, Liang Y, Hsu J, Chen CT, Beaupre D, Chang BY.
Kuo HP, et al. Among authors: apatira m.
Am J Cancer Res. 2016 Nov 1;6(11):2489-2501. eCollection 2016.
Am J Cancer Res. 2016.
PMID: 27904766
Free PMC article.
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Combination of Ibrutinib and ABT-199 in Diffuse Large B-Cell Lymphoma and Follicular Lymphoma.
Kuo HP, Ezell SA, Schweighofer KJ, Cheung LWK, Hsieh S, Apatira M, Sirisawad M, Eckert K, Hsu SJ, Chen CT, Beaupre DM, Versele M, Chang BY.
Kuo HP, et al. Among authors: apatira m.
Mol Cancer Ther. 2017 Jul;16(7):1246-1256. doi: 10.1158/1535-7163.MCT-16-0555. Epub 2017 Apr 20.
Mol Cancer Ther. 2017.
PMID: 28428442
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CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML).
Kelly LM, Yu JC, Boulton CL, Apatira M, Li J, Sullivan CM, Williams I, Amaral SM, Curley DP, Duclos N, Neuberg D, Scarborough RM, Pandey A, Hollenbach S, Abe K, Lokker NA, Gilliland DG, Giese NA.
Kelly LM, et al. Among authors: apatira m.
Cancer Cell. 2002 Jun;1(5):421-32. doi: 10.1016/s1535-6108(02)00070-3.
Cancer Cell. 2002.
PMID: 12124172
Free article.
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Efficacy of the novel selective platelet-derived growth factor receptor antagonist CT52923 on cellular proliferation, migration, and suppression of neointima following vascular injury.
Yu JC, Lokker NA, Hollenbach S, Apatira M, Li J, Betz A, Sedlock D, Oda S, Nomoto Y, Matsuno K, Ide S, Tsukuda E, Giese NA.
Yu JC, et al. Among authors: apatira m.
J Pharmacol Exp Ther. 2001 Sep;298(3):1172-8.
J Pharmacol Exp Ther. 2001.
PMID: 11504817
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