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CD4+ T cell calibration of antigen-presenting cells optimizes antiviral CD8+ T cell immunity.
Gressier E, Schulte-Schrepping J, Petrov L, Brumhard S, Stubbemann P, Hiller A, Obermayer B, Spitzer J, Kostevc T, Whitney PG, Bachem A, Odainic A, van de Sandt C, Nguyen THO, Ashhurst T, Wilson K, Oates CVL, Gearing LJ, Meischel T, Hochheiser K, Greyer M, Clarke M, Kreutzenbeck M, Gabriel SS, Kastenmüller W, Kurts C, Londrigan SL, Kallies A, Kedzierska K, Hertzog PJ, Latz E, Chen YE, Radford KJ, Chopin M, Schroeder J, Kurth F, Gebhardt T, Sander LE, Sawitzki B, Schultze JL, Schmidt SV, Bedoui S. Gressier E, et al. Among authors: van de sandt c. Nat Immunol. 2023 Jun;24(6):979-990. doi: 10.1038/s41590-023-01517-x. Epub 2023 May 15. Nat Immunol. 2023. PMID: 37188942
T Cell Epitope Discovery in the Context of Distinct and Unique Indigenous HLA Profiles.
Hensen L, Illing PT, Rowntree LC, Davies J, Miller A, Tong SYC, Habel JR, van de Sandt CE, Flanagan KL, Purcell AW, Kedzierska K, Clemens EB. Hensen L, et al. Among authors: van de sandt ce. Front Immunol. 2022 May 6;13:812393. doi: 10.3389/fimmu.2022.812393. eCollection 2022. Front Immunol. 2022. PMID: 35603215 Free PMC article. Review.
CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph.
Hensen L, Illing PT, Bridie Clemens E, Nguyen THO, Koutsakos M, van de Sandt CE, Mifsud NA, Nguyen AT, Szeto C, Chua BY, Halim H, Rizzetto S, Luciani F, Loh L, Grant EJ, Saunders PM, Brooks AG, Rockman S, Kotsimbos TC, Cheng AC, Richards M, Westall GP, Wakim LM, Loudovaris T, Mannering SI, Elliott M, Tangye SG, Jackson DC, Flanagan KL, Rossjohn J, Gras S, Davies J, Miller A, Tong SYC, Purcell AW, Kedzierska K. Hensen L, et al. Among authors: van de sandt ce. Nat Commun. 2021 May 18;12(1):2931. doi: 10.1038/s41467-021-23212-x. Nat Commun. 2021. PMID: 34006841 Free PMC article.
Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph.
van de Sandt CE, Clemens EB, Grant EJ, Rowntree LC, Sant S, Halim H, Crowe J, Cheng AC, Kotsimbos TC, Richards M, Miller A, Tong SYC, Rossjohn J, Nguyen THO, Gras S, Chen W, Kedzierska K. van de Sandt CE, et al. Nat Commun. 2019 Dec 6;10(1):5579. doi: 10.1038/s41467-019-13346-4. Nat Commun. 2019. PMID: 31811120 Free PMC article.
HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8+ T cells.
Sant S, Quiñones-Parra SM, Koutsakos M, Grant EJ, Loudovaris T, Mannering SI, Crowe J, van de Sandt CE, Rimmelzwaan GF, Rossjohn J, Gras S, Loh L, Nguyen THO, Kedzierska K. Sant S, et al. PLoS Pathog. 2020 Aug 4;16(8):e1008714. doi: 10.1371/journal.ppat.1008714. eCollection 2020 Aug. PLoS Pathog. 2020. PMID: 32750095 Free PMC article.
Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients.
Nguyen THO, Koutsakos M, van de Sandt CE, Crawford JC, Loh L, Sant S, Grzelak L, Allen EK, Brahm T, Clemens EB, Auladell M, Hensen L, Wang Z, Nüssing S, Jia X, Günther P, Wheatley AK, Kent SJ, Aban M, Deng YM, Laurie KL, Hurt AC, Gras S, Rossjohn J, Crowe J, Xu J, Jackson D, Brown LE, La Gruta N, Chen W, Doherty PC, Turner SJ, Kotsimbos TC, Thomas PG, Cheng AC, Kedzierska K. Nguyen THO, et al. Among authors: van de sandt ce. Nat Commun. 2021 May 11;12(1):2691. doi: 10.1038/s41467-021-23018-x. Nat Commun. 2021. PMID: 33976217 Free PMC article.
Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality.
Quinn KM, Hussain T, Kraus F, Formosa LE, Lam WK, Dagley MJ, Saunders EC, Assmus LM, Wynne-Jones E, Loh L, van de Sandt CE, Cooper L, Good-Jacobson KL, Kedzierska K, Mackay LK, McConville MJ, Ramm G, Ryan MT, La Gruta NL. Quinn KM, et al. Among authors: van de sandt ce. Nat Commun. 2020 Jun 5;11(1):2857. doi: 10.1038/s41467-020-16633-7. Nat Commun. 2020. PMID: 32504069 Free PMC article.
Suboptimal SARS-CoV-2-specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype.
Habel JR, Nguyen THO, van de Sandt CE, Juno JA, Chaurasia P, Wragg K, Koutsakos M, Hensen L, Jia X, Chua B, Zhang W, Tan HX, Flanagan KL, Doolan DL, Torresi J, Chen W, Wakim LM, Cheng AC, Doherty PC, Petersen J, Rossjohn J, Wheatley AK, Kent SJ, Rowntree LC, Kedzierska K. Habel JR, et al. Among authors: van de sandt ce. Proc Natl Acad Sci U S A. 2020 Sep 29;117(39):24384-24391. doi: 10.1073/pnas.2015486117. Epub 2020 Sep 10. Proc Natl Acad Sci U S A. 2020. PMID: 32913053 Free PMC article.
51 results