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A common genetic defect in nicotine metabolism decreases risk for dependence and lowers cigarette consumption.
Tyndale RF, Pianezza ML, Sellers EM. Tyndale RF, et al. Nicotine Tob Res. 1999;1 Suppl 2:S63-7; discussion S69-70. doi: 10.1080/14622299050011831. Nicotine Tob Res. 1999. PMID: 11768189 Review.
This paper outlines how genetic variation in the CYP2A6 gene may protect individuals from becoming nicotine-dependent smokers, and if dependent, how impairment of the CYP2A6 gene function decreases the number of cigarettes consumed by smokers (Pianezza M, Sellers EM, Tyndale …
This paper outlines how genetic variation in the CYP2A6 gene may protect individuals from becoming nicotine-dependent smokers, and if depend …
Organic cation transporter variation and response to smoking cessation therapies.
Bergen AW, Javitz HS, Krasnow R, Michel M, Nishita D, Conti DV, Edlund CK, Kwok PY, McClure JB, Kim RB, Hall SM, Tyndale RF, Baker TB, Benowitz NL, Swan GE. Bergen AW, et al. Among authors: tyndale rf. Nicotine Tob Res. 2014 Dec;16(12):1638-46. doi: 10.1093/ntr/ntu161. Epub 2014 Aug 20. Nicotine Tob Res. 2014. PMID: 25143296 Free PMC article. Clinical Trial.
The Nicotine Metabolite Ratio is Associated With Early Smoking Abstinence Even After Controlling for Factors That Influence the Nicotine Metabolite Ratio.
Chenoweth MJ, Schnoll RA, Novalen M, Hawk LW Jr, George TP, Cinciripini PM, Lerman C, Tyndale RF. Chenoweth MJ, et al. Among authors: tyndale rf. Nicotine Tob Res. 2016 Apr;18(4):491-5. doi: 10.1093/ntr/ntv125. Epub 2015 Jun 11. Nicotine Tob Res. 2016. PMID: 26069034 Free PMC article. Clinical Trial.
432 results