Bagnall JS - Search Results

1

Overexpression of IκB⍺ modulates NF-κB activation of inflammatory target gene expression.

Downton P, Bagnall JS, England H, Spiller DG, Humphreys NE, Jackson DA, Paszek P, White MRH, Adamson AD. Downton P, et al. Among authors: bagnall js. Front Mol Biosci. 2023 May 9;10:1187187. doi: 10.3389/fmolb.2023.1187187. eCollection 2023. Front Mol Biosci. 2023. PMID: 37228587 Free PMC article.

2

Tight control of hypoxia-inducible factor-α transient dynamics is essential for cell survival in hypoxia.

Bagnall J, Leedale J, Taylor SE, Spiller DG, White MR, Sharkey KJ, Bearon RN, Sée V. Bagnall J, et al. J Biol Chem. 2014 Feb 28;289(9):5549-64. doi: 10.1074/jbc.M113.500405. Epub 2014 Jan 6. J Biol Chem. 2014. PMID: 24394419 Free PMC article.

3

Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer.

Bagnall J, Boddington C, Boyd J, Brignall R, Rowe W, Jones NA, Schmidt L, Spiller DG, White MR, Paszek P. Bagnall J, et al. Integr Biol (Camb). 2015 Jun;7(6):713-25. doi: 10.1039/c5ib00067j. Epub 2015 May 20. Integr Biol (Camb). 2015. PMID: 25990200

4

Inflammasome-dependent IL-1β release depends upon membrane permeabilisation.

Martín-Sánchez F, Diamond C, Zeitler M, Gomez AI, Baroja-Mazo A, Bagnall J, Spiller D, White M, Daniels MJ, Mortellaro A, Peñalver M, Paszek P, Steringer JP, Nickel W, Brough D, Pelegrín P. Martín-Sánchez F, et al. Cell Death Differ. 2016 Jul;23(7):1219-31. doi: 10.1038/cdd.2015.176. Epub 2016 Feb 12. Cell Death Differ. 2016. PMID: 26868913 Free PMC article.

5

Investigating IL-1β Secretion Using Real-Time Single-Cell Imaging.

Diamond C, Bagnall J, Spiller DG, White MR, Mortellaro A, Paszek P, Brough D. Diamond C, et al. Methods Mol Biol. 2016;1417:75-88. doi: 10.1007/978-1-4939-3566-6_4. Methods Mol Biol. 2016. PMID: 27221482

6

Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states.

Adamson A, Boddington C, Downton P, Rowe W, Bagnall J, Lam C, Maya-Mendoza A, Schmidt L, Harper CV, Spiller DG, Rand DA, Jackson DA, White MR, Paszek P. Adamson A, et al. Nat Commun. 2016 Jul 6;7:12057. doi: 10.1038/ncomms12057. Nat Commun. 2016. PMID: 27381163 Free PMC article.

7

Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models.

Daniels MJ, Rivers-Auty J, Schilling T, Spencer NG, Watremez W, Fasolino V, Booth SJ, White CS, Baldwin AG, Freeman S, Wong R, Latta C, Yu S, Jackson J, Fischer N, Koziel V, Pillot T, Bagnall J, Allan SM, Paszek P, Galea J, Harte MK, Eder C, Lawrence CB, Brough D. Daniels MJ, et al. Nat Commun. 2016 Aug 11;7:12504. doi: 10.1038/ncomms12504. Nat Commun. 2016. PMID: 27509875 Free PMC article.

8

Anti-inflammatory effects of infliximab in mice are independent of tumour necrosis factor α neutralization.

Assas MB, Levison SE, Little M, England H, Battrick L, Bagnall J, McLaughlin JT, Paszek P, Else KJ, Pennock JL. Assas MB, et al. Clin Exp Immunol. 2017 Feb;187(2):225-233. doi: 10.1111/cei.12872. Epub 2016 Nov 23. Clin Exp Immunol. 2017. PMID: 27669117 Free PMC article.

9

Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation.

Phillips NE, Manning CS, Pettini T, Biga V, Marinopoulou E, Stanley P, Boyd J, Bagnall J, Paszek P, Spiller DG, White MR, Goodfellow M, Galla T, Rattray M, Papalopulu N. Phillips NE, et al. Elife. 2016 Oct 4;5:e16118. doi: 10.7554/eLife.16118. Elife. 2016. PMID: 27700985 Free PMC article.

10

Integration of Kinase and Calcium Signaling at the Level of Chromatin Underlies Inducible Gene Activation in T Cells.

Brignall R, Cauchy P, Bevington SL, Gorman B, Pisco AO, Bagnall J, Boddington C, Rowe W, England H, Rich K, Schmidt L, Dyer NP, Travis MA, Ott S, Jackson DA, Cockerill PN, Paszek P. Brignall R, et al. J Immunol. 2017 Oct 15;199(8):2652-2667. doi: 10.4049/jimmunol.1602033. Epub 2017 Sep 13. J Immunol. 2017. PMID: 28904128 Free PMC article.

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