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Neutrophil extracellular traps and extracellular histones potentiate IL-17 inflammation in periodontitis.
Kim TS, Silva LM, Theofilou VI, Greenwell-Wild T, Li L, Williams DW, Ikeuchi T, Brenchley L; NIDCD/NIDCR Genomics and Computational Biology Core; Bugge TH, Diaz PI, Kaplan MJ, Carmona-Rivera C, Moutsopoulos NM. Kim TS, et al. Among authors: ikeuchi t. J Exp Med. 2023 Sep 4;220(9):e20221751. doi: 10.1084/jem.20221751. Epub 2023 Jun 1. J Exp Med. 2023. PMID: 37261457 Free PMC article.
A dysbiotic microbiome triggers TH17 cells to mediate oral mucosal immunopathology in mice and humans.
Dutzan N, Kajikawa T, Abusleme L, Greenwell-Wild T, Zuazo CE, Ikeuchi T, Brenchley L, Abe T, Hurabielle C, Martin D, Morell RJ, Freeman AF, Lazarevic V, Trinchieri G, Diaz PI, Holland SM, Belkaid Y, Hajishengallis G, Moutsopoulos NM. Dutzan N, et al. Among authors: ikeuchi t. Sci Transl Med. 2018 Oct 17;10(463):eaat0797. doi: 10.1126/scitranslmed.aat0797. Sci Transl Med. 2018. PMID: 30333238 Free PMC article. Clinical Trial.
Dissociation of murine oral mucosal tissues for single cell applications.
Ikeuchi T, Akhi R, Cardona Rodriguez B, Fraser D, Williams D, Kim TS, Greenwell-Wild T, Overmiller A, Morasso M, Moutsopoulos N. Ikeuchi T, et al. J Immunol Methods. 2024 Feb;525:113605. doi: 10.1016/j.jim.2023.113605. Epub 2023 Dec 22. J Immunol Methods. 2024. PMID: 38142927
Epithelial-derived interleukin-23 promotes oral mucosal immunopathology.
Kim TS, Ikeuchi T, Theofilou VI, Williams DW, Greenwell-Wild T, June A, Adade EE, Li L, Abusleme L, Dutzan N, Yuan Y, Brenchley L, Bouladoux N, Sakamachi Y; NIDCD/NIDCR Genomics and Computational Biology Core; Palmer RJ Jr, Iglesias-Bartolome R, Trinchieri G, Garantziotis S, Belkaid Y, Valm AM, Diaz PI, Holland SM, Moutsopoulos NM. Kim TS, et al. Among authors: ikeuchi t. Immunity. 2024 Apr 9;57(4):859-875.e11. doi: 10.1016/j.immuni.2024.02.020. Epub 2024 Mar 20. Immunity. 2024. PMID: 38513665
Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut.
Das A, Martinez-Ruiz GU, Bouladoux N, Stacy A, Moraly J, Vega-Sendino M, Zhao Y, Lavaert M, Ding Y, Morales-Sanchez A, Harly C, Seedhom MO, Chari R, Awasthi P, Ikeuchi T, Wang Y, Zhu J, Moutsopoulos NM, Chen W, Yewdell JW, Shapiro VS, Ruiz S, Taylor N, Belkaid Y, Bhandoola A. Das A, et al. Among authors: ikeuchi t. Immunity. 2024 May 14;57(5):1019-1036.e9. doi: 10.1016/j.immuni.2024.04.001. Epub 2024 Apr 26. Immunity. 2024. PMID: 38677292
Cell adhesion protein fibulin-7 and its C-terminal fragment negatively regulate monocyte and macrophage migration and functions in vitro and in vivo.
Sarangi PP, Chakraborty P, Dash SP, Ikeuchi T, de Vega S, Ambatipudi K, Wahl L, Yamada Y. Sarangi PP, et al. Among authors: ikeuchi t. FASEB J. 2018 Sep;32(9):4889-4898. doi: 10.1096/fj.201700686RRR. Epub 2018 Apr 10. FASEB J. 2018. PMID: 29634368 Free PMC article.
Thus, these results suggest that Fbln7 and Fbln7-C could modulate the activity of immune cells and have therapeutic potential for inflammatory diseases.-Sarangi, P. P., Chakraborty, P., Dash, S. P., Ikeuchi, T., de Vega, S., Ambatipudi, K., Wahl, L., Yamada, Y. Cell …
Thus, these results suggest that Fbln7 and Fbln7-C could modulate the activity of immune cells and have therapeutic potential for inflammato …
Advances in Oncology in US and Japan: Focusing on Cancer and Infectious Diseases.
Nakano H, Miyamoto T, Janjigian YY, Mine S, Mitsuya H, Ueno NT, Sharon E, Sakai S, Timmer WC, Nakabo S, Ikeuchi T, Fujiwara S, Kinjo M, Inuzuka T, Kume H, Shirai K, Yamaguchi N, Takabe K, Takebe N. Nakano H, et al. Among authors: ikeuchi t. World J Oncol. 2021 Dec;12(6):183-194. doi: 10.14740/wjon1422. Epub 2021 Dec 13. World J Oncol. 2021. PMID: 35059078 Free PMC article. Review.
695 results