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Venetoclax is a potent hepsin inhibitor that reduces the metastatic and prothrombotic phenotypes of hepsin-expressing colorectal cancer cells.
Front Mol Biosci. 2023 May 19;10:1182925. doi: 10.3389/fmolb.2023.1182925. eCollection 2023.
Front Mol Biosci. 2023.
PMID: 37275957
Free PMC article.
Dual Role of DUOX1-Derived Reactive Oxygen Species in Melanoma.
Pardo-Sánchez I, Ibañez-Molero S, García-Moreno D, Mulero V.
Pardo-Sánchez I, et al.
Antioxidants (Basel). 2023 Mar 13;12(3):708. doi: 10.3390/antiox12030708.
Antioxidants (Basel). 2023.
PMID: 36978957
Free PMC article.
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Zebrafish Models to Study the Crosstalk between Inflammation and NADPH Oxidase-Derived Oxidative Stress in Melanoma.
Pardo-Sánchez I, García-Moreno D, Mulero V.
Pardo-Sánchez I, et al.
Antioxidants (Basel). 2022 Jun 28;11(7):1277. doi: 10.3390/antiox11071277.
Antioxidants (Basel). 2022.
PMID: 35883768
Free PMC article.
Review.
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The vitamin B6-regulated enzymes PYGL and G6PD fuel NADPH oxidases to promote skin inflammation.
Martínez-Navarro FJ, Martínez-Morcillo FJ, López-Muñoz A, Pardo-Sánchez I, Martínez-Menchón T, Corbalán-Vélez R, Cayuela ML, Pérez-Oliva AB, García-Moreno D, Mulero V.
Martínez-Navarro FJ, et al. Among authors: pardo sanchez i.
Dev Comp Immunol. 2020 Jul;108:103666. doi: 10.1016/j.dci.2020.103666. Epub 2020 Feb 29.
Dev Comp Immunol. 2020.
PMID: 32126244
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Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1.
Tyrkalska SD, Pérez-Oliva AB, Rodríguez-Ruiz L, Martínez-Morcillo FJ, Alcaraz-Pérez F, Martínez-Navarro FJ, Lachaud C, Ahmed N, Schroeder T, Pardo-Sánchez I, Candel S, López-Muñoz A, Choudhuri A, Rossmann MP, Zon LI, Cayuela ML, García-Moreno D, Mulero V.
Tyrkalska SD, et al. Among authors: pardo sanchez i.
Immunity. 2019 Jul 16;51(1):50-63.e5. doi: 10.1016/j.immuni.2019.05.005. Epub 2019 Jun 4.
Immunity. 2019.
PMID: 31174991
Free PMC article.
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Suramin, a drug for the treatment of trypanosomiasis, reduces the prothrombotic and metastatic phenotypes of colorectal cancer cells by inhibiting hepsin.
Zaragoza-Huesca D, Rodenas MC, Peñas-Martínez J, Pardo-Sánchez I, Peña-García J, Espín S, Ricote G, Nieto A, García-Molina F, Vicente V, Lozano ML, Carmona-Bayonas A, Mulero V, Pérez-Sánchez H, Martínez-Martínez I.
Zaragoza-Huesca D, et al. Among authors: pardo sanchez i.
Biomed Pharmacother. 2023 Dec;168:115814. doi: 10.1016/j.biopha.2023.115814. Epub 2023 Oct 31.
Biomed Pharmacother. 2023.
PMID: 37918256
Free article.
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