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Amino acid homeostasis is a target of metformin therapy.
Forteath C, Mordi I, Nisr R, Gutierrez-Lara EJ, Alqurashi N, Phair IR, Cameron AR, Beall C, Bahr I, Mohan M, Wong AKF, Dihoum A, Mohammad A, Palmer CNA, Lamont D, Sakamoto K, Viollet B, Foretz M, Lang CC, Rena G. Forteath C, et al. Among authors: rena g. Mol Metab. 2023 Aug;74:101750. doi: 10.1016/j.molmet.2023.101750. Epub 2023 Jun 9. Mol Metab. 2023. PMID: 37302544 Free PMC article. Clinical Trial.
Cellular responses to the metal-binding properties of metformin.
Logie L, Harthill J, Patel K, Bacon S, Hamilton DL, Macrae K, McDougall G, Wang HH, Xue L, Jiang H, Sakamoto K, Prescott AR, Rena G. Logie L, et al. Among authors: rena g. Diabetes. 2012 Jun;61(6):1423-33. doi: 10.2337/db11-0961. Epub 2012 Apr 9. Diabetes. 2012. PMID: 22492524 Free PMC article.
Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug.
Cameron AR, Logie L, Patel K, Bacon S, Forteath C, Harthill J, Roberts A, Sutherland C, Stewart D, Viollet B, Sakamoto K, McDougall G, Foretz M, Rena G. Cameron AR, et al. Among authors: rena g. Biochim Biophys Acta. 2016 Aug;1862(8):1412-22. doi: 10.1016/j.bbadis.2016.04.015. Epub 2016 Apr 27. Biochim Biophys Acta. 2016. PMID: 27130437 Free PMC article.
Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status.
Cameron AR, Morrison VL, Levin D, Mohan M, Forteath C, Beall C, McNeilly AD, Balfour DJ, Savinko T, Wong AK, Viollet B, Sakamoto K, Fagerholm SC, Foretz M, Lang CC, Rena G. Cameron AR, et al. Among authors: rena g. Circ Res. 2016 Aug 19;119(5):652-65. doi: 10.1161/CIRCRESAHA.116.308445. Epub 2016 Jul 14. Circ Res. 2016. PMID: 27418629 Free PMC article. Clinical Trial.
Metformin selectively targets redox control of complex I energy transduction.
Cameron AR, Logie L, Patel K, Erhardt S, Bacon S, Middleton P, Harthill J, Forteath C, Coats JT, Kerr C, Curry H, Stewart D, Sakamoto K, Repiščák P, Paterson MJ, Hassinen I, McDougall G, Rena G. Cameron AR, et al. Among authors: rena g. Redox Biol. 2018 Apr;14:187-197. doi: 10.1016/j.redox.2017.08.018. Epub 2017 Aug 26. Redox Biol. 2018. PMID: 28942196 Free PMC article.
48 results