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BLM overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor-resistant BRCA-mutant ovarian cancer.
Gupta N, Huang TT, Nair JR, An D, Zurcher G, Lampert EJ, McCoy A, Cimino-Mathews A, Swisher EM, Radke MR, Lockwood CM, Reichel JB, Chiang CY, Wilson KM, Cheng KC, Nousome D, Lee JM. Gupta N, et al. Sci Transl Med. 2023 Jun 21;15(701):eadd7872. doi: 10.1126/scitranslmed.add7872. Epub 2023 Jun 21. Sci Transl Med. 2023. PMID: 37343085 Free PMC article. Clinical Trial.
Carving a niche for immunotherapy in ovarian cancer.
Gupta N, Lampert E, Lee JM. Gupta N, et al. Oncotarget. 2021 Jan 5;12(1):4-7. doi: 10.18632/oncotarget.27864. eCollection 2021 Jan 5. Oncotarget. 2021. PMID: 33456707 Free PMC article. No abstract available.
A phase 1 study to assess the absolute bioavailability, mass balance, pharmacokinetics, metabolism, and excretion of [14C]-mobocertinib, an oral inhibitor of EGFR exon 20 insertion mutations, in healthy participants.
Hanley MJ, Zhang S, Griffin R, Zhu SX, Fram RJ, Lin J, Venkatakrishnan K, Gupta N. Hanley MJ, et al. Among authors: gupta n. Invest New Drugs. 2024 May 24. doi: 10.1007/s10637-024-01446-y. Online ahead of print. Invest New Drugs. 2024. PMID: 38789848
Moving the needle for oncology dose optimization: A call for action.
Venkatakrishnan K, Jayachandran P, Seo SK, van der Graaf PH, Wagner JA, Gupta N. Venkatakrishnan K, et al. Among authors: gupta n. CPT Pharmacometrics Syst Pharmacol. 2024 May 22. doi: 10.1002/psp4.13157. Online ahead of print. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38778466 Free article. No abstract available.
8,242 results