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A rapid cell-free expression and screening platform for antibody discovery.
Hunt AC, Vögeli B, Hassan AO, Guerrero L, Kightlinger W, Yoesep DJ, Krüger A, DeWinter M, Diamond MS, Karim AS, Jewett MC. Hunt AC, et al. Among authors: kruger a. Nat Commun. 2023 Jul 3;14(1):3897. doi: 10.1038/s41467-023-38965-w. Nat Commun. 2023. PMID: 37400446 Free PMC article.
Cell-free styrene biosynthesis at high titers.
Grubbe WS, Rasor BJ, Krüger A, Jewett MC, Karim AS. Grubbe WS, et al. Among authors: kruger a. Metab Eng. 2020 Sep;61:89-95. doi: 10.1016/j.ymben.2020.05.009. Epub 2020 Jun 2. Metab Eng. 2020. PMID: 32502620
Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice.
Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, Kozodoy L, Carter L, Ravichandran R, Green LB, Matochko WL, Thomson CA, Vögeli B, Krüger A, VanBlargan LA, Chen RE, Ying B, Bailey AL, Kafai NM, Boyken SE, Ljubetič A, Edman N, Ueda G, Chow CM, Johnson M, Addetia A, Navarro MJ, Panpradist N, Gale M Jr, Freedman BS, Bloom JD, Ruohola-Baker H, Whelan SPJ, Stewart L, Diamond MS, Veesler D, Jewett MC, Baker D. Hunt AC, et al. Among authors: kruger a. Sci Transl Med. 2022 May 25;14(646):eabn1252. doi: 10.1126/scitranslmed.abn1252. Epub 2022 May 25. Sci Transl Med. 2022. PMID: 35412328 Free PMC article.
Community science designed ribosomes with beneficial phenotypes.
Krüger A, Watkins AM, Wellington-Oguri R, Romano J, Kofman C, DeFoe A, Kim Y, Anderson-Lee J, Fisker E, Townley J; Eterna Participants; d'Aquino AE, Das R, Jewett MC. Krüger A, et al. Nat Commun. 2023 Feb 21;14(1):961. doi: 10.1038/s41467-023-35827-3. Nat Commun. 2023. PMID: 36810740 Free PMC article.
1,114 results