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Application of ultrasensitive digital ELISA for p24 enables improved evaluation of HIV-1 reservoir diversity and growth kinetics in viral outgrowth assays.
Kuzmichev YV, Lackman-Smith C, Bakkour S, Wiegand A, Bale MJ, Musick A, Bernstein W, Aronson N, Ake J, Tovanabutra S, Stone M, Ptak RG, Kearney MF, Busch MP, Wonderlich ER, Kulpa DA. Kuzmichev YV, et al. Among authors: bakkour s. Sci Rep. 2023 Jul 6;13(1):10958. doi: 10.1038/s41598-023-37223-9. Sci Rep. 2023. PMID: 37414788 Free PMC article.
A highly multiplexed droplet digital PCR assay to measure the intact HIV-1 proviral reservoir.
Levy CN, Hughes SM, Roychoudhury P, Reeves DB, Amstuz C, Zhu H, Huang ML, Wei Y, Bull ME, Cassidy NAJ, McClure J, Frenkel LM, Stone M, Bakkour S, Wonderlich ER, Busch MP, Deeks SG, Schiffer JT, Coombs RW, Lehman DA, Jerome KR, Hladik F. Levy CN, et al. Among authors: bakkour s. Cell Rep Med. 2021 Apr 12;2(4):100243. doi: 10.1016/j.xcrm.2021.100243. eCollection 2021 Apr 20. Cell Rep Med. 2021. PMID: 33948574 Free PMC article.
Assessing the Suitability of Next-Generation Viral Outgrowth Assays to Measure Human Immunodeficiency Virus 1 Latent Reservoir Size.
Stone M, Rosenbloom DIS, Bacchetti P, Deng X, Dimapasoc M, Keating S, Bakkour S, Richman DD, Mellors JW, Deeks SG, Lai J, Beg S, Siliciano JD, Pagliuzza A, Chomont N, Lackman-Smith C, Ptak RG, Busch MP. Stone M, et al. Among authors: bakkour s. J Infect Dis. 2021 Oct 13;224(7):1209-1218. doi: 10.1093/infdis/jiaa089. J Infect Dis. 2021. PMID: 32147687 Free PMC article.
Comparison of Detection Limits of Fourth- and Fifth-Generation Combination HIV Antigen-Antibody, p24 Antigen, and Viral Load Assays on Diverse HIV Isolates.
Stone M, Bainbridge J, Sanchez AM, Keating SM, Pappas A, Rountree W, Todd C, Bakkour S, Manak M, Peel SA, Coombs RW, Ramos EM, Shriver MK, Contestable P, Nair SV, Wilson DH, Stengelin M, Murphy G, Hewlett I, Denny TN, Busch MP. Stone M, et al. Among authors: bakkour s. J Clin Microbiol. 2018 Jul 26;56(8):e02045-17. doi: 10.1128/JCM.02045-17. Print 2018 Aug. J Clin Microbiol. 2018. PMID: 29793968 Free PMC article.
Automated Multireplicate Quantification of Persistent HIV-1 Viremia in Individuals on Antiretroviral Therapy.
Jacobs JL, Tosiano MA, Koontz DL, Staines B, Worlock A, Harrington K, Bakkour S, Stone M, Shutt K, Busch MP, Mellors JW. Jacobs JL, et al. Among authors: bakkour s. J Clin Microbiol. 2020 Nov 18;58(12):e01442-20. doi: 10.1128/JCM.01442-20. Print 2020 Nov 18. J Clin Microbiol. 2020. PMID: 32967899 Free PMC article.
Such assays require multistep manual methods, and their low throughput limits the capacity to monitor the effects of interventions on persistent viremia. Recently, S. Bakkour, X. Deng, P. Bacchetti, E. Grebe, et al. (J Clin Microbiol 58:e01400-20, 2020, https://doi. …
Such assays require multistep manual methods, and their low throughput limits the capacity to monitor the effects of interventions on persis …
Blood Center Testing Allows the Detection and Rapid Treatment of Acute and Recent HIV Infection.
van den Berg K, Vermeulen M, Bakkour S, Stone M, Jacobs G, Nyoni C, Barker C, McClure C, Creel D, Grebe E, Roubinian N, Jentsch U, Custer B, Busch MP, Murphy EL, On Behalf Of The Recipient Epidemiology And Donor Evaluation Study Reds-Iii South Africa International Program. van den Berg K, et al. Among authors: bakkour s. Viruses. 2022 Oct 23;14(11):2326. doi: 10.3390/v14112326. Viruses. 2022. PMID: 36366424 Free PMC article.
Rapid development of HIV elite control in a patient with acute infection.
Morley D, Lambert JS, Hogan LE, De Gascun C, Redmond N, Rutishauser RL, Thanh C, Gibson EA, Hobbs K, Bakkour S, Busch MP, Farrell J, McGetrick P, Henrich TJ. Morley D, et al. Among authors: bakkour s. BMC Infect Dis. 2019 Sep 18;19(1):815. doi: 10.1186/s12879-019-4374-8. BMC Infect Dis. 2019. PMID: 31533639 Free PMC article.
58 results