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TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry.
Baggen J, Jacquemyn M, Persoons L, Vanstreels E, Pye VE, Wrobel AG, Calvaresi V, Martin SR, Roustan C, Cronin NB, Reading E, Thibaut HJ, Vercruysse T, Maes P, De Smet F, Yee A, Nivitchanyong T, Roell M, Franco-Hernandez N, Rhinn H, Mamchak AA, Ah Young-Chapon M, Brown E, Cherepanov P, Daelemans D. Baggen J, et al. Cell. 2023 Aug 3;186(16):3427-3442.e22. doi: 10.1016/j.cell.2023.06.005. Epub 2023 Jul 7. Cell. 2023. PMID: 37421949 Free PMC article.
Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2.
Baggen J, Persoons L, Vanstreels E, Jansen S, Van Looveren D, Boeckx B, Geudens V, De Man J, Jochmans D, Wauters J, Wauters E, Vanaudenaerde BM, Lambrechts D, Neyts J, Dallmeier K, Thibaut HJ, Jacquemyn M, Maes P, Daelemans D. Baggen J, et al. Nat Genet. 2021 Apr;53(4):435-444. doi: 10.1038/s41588-021-00805-2. Epub 2021 Mar 8. Nat Genet. 2021. PMID: 33686287
Cellular host factors for SARS-CoV-2 infection.
Baggen J, Vanstreels E, Jansen S, Daelemans D. Baggen J, et al. Nat Microbiol. 2021 Oct;6(10):1219-1232. doi: 10.1038/s41564-021-00958-0. Epub 2021 Sep 1. Nat Microbiol. 2021. PMID: 34471255 Review.
Sialic acid-dependent cell entry of human enterovirus D68.
Liu Y, Sheng J, Baggen J, Meng G, Xiao C, Thibaut HJ, van Kuppeveld FJ, Rossmann MG. Liu Y, et al. Among authors: baggen j. Nat Commun. 2015 Nov 13;6:8865. doi: 10.1038/ncomms9865. Nat Commun. 2015. PMID: 26563423 Free PMC article.
Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68.
Sun L, Meijer A, Froeyen M, Zhang L, Thibaut HJ, Baggen J, George S, Vernachio J, van Kuppeveld FJ, Leyssen P, Hilgenfeld R, Neyts J, Delang L. Sun L, et al. Among authors: baggen j. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5. doi: 10.1128/AAC.01375-15. Epub 2015 Sep 14. Antimicrob Agents Chemother. 2015. PMID: 26369972 Free PMC article.
PLA2G16 represents a switch between entry and clearance of Picornaviridae.
Staring J, von Castelmur E, Blomen VA, van den Hengel LG, Brockmann M, Baggen J, Thibaut HJ, Nieuwenhuis J, Janssen H, van Kuppeveld FJ, Perrakis A, Carette JE, Brummelkamp TR. Staring J, et al. Among authors: baggen j. Nature. 2017 Jan 19;541(7637):412-416. doi: 10.1038/nature21032. Epub 2017 Jan 11. Nature. 2017. PMID: 28077878
44 results