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Page 1
Discovery of Potent and Selective Covalent Inhibitors of HER2WT and HER2YVMA.
Hicken EJ, Brown K, Dwulet NC, Gaudino JJ, Hansen EP, Hartley DP, Kowalski JP, Laird ER, Lazzara NC, Li B, Mou TC, Mutryn MF, Oko L, Pajk S, Pipal RW, Rosen RZ, Shelp R, Singh A, Wang J, Wise CE, Wong C, Wong JY. Hicken EJ, et al. Among authors: mutryn mf. J Med Chem. 2024 May 31. doi: 10.1021/acs.jmedchem.4c00978. Online ahead of print. J Med Chem. 2024. PMID: 38820338
Smooth muscle-derived adventitial progenitor cells promote key cell type transitions controlling plaque stability in atherosclerosis in a Klf4-dependent manner.
Dubner AM, Lu S, Jolly AJ, Strand KA, Mutryn MF, Hinthorn T, Noble T, Nemenoff RA, Moulton KS, Majesky MW, Weiser-Evans MC. Dubner AM, et al. Among authors: mutryn mf. bioRxiv [Preprint]. 2023 Jul 19:2023.07.18.549539. doi: 10.1101/2023.07.18.549539. bioRxiv. 2023. PMID: 37503181 Free PMC article. Preprint.
High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog): Central Role for PTEN in 5-Azacytidine Protection Against Pathological Vascular Remodeling.
Strand KA, Lu S, Mutryn MF, Li L, Zhou Q, Enyart BT, Jolly AJ, Dubner AM, Moulton KS, Nemenoff RA, Koch KA, LaBarbera DV, Weiser-Evans MCM. Strand KA, et al. Among authors: mutryn mf. Arterioscler Thromb Vasc Biol. 2020 Aug;40(8):1854-1869. doi: 10.1161/ATVBAHA.120.314458. Epub 2020 Jun 25. Arterioscler Thromb Vasc Biol. 2020. PMID: 32580634 Free PMC article.
PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling-Brief Report.
Lu S, Strand KA, Mutryn MF, Tucker RM, Jolly AJ, Furgeson SB, Moulton KS, Nemenoff RA, Weiser-Evans MCM. Lu S, et al. Among authors: mutryn mf. Arterioscler Thromb Vasc Biol. 2020 Feb;40(2):394-403. doi: 10.1161/ATVBAHA.119.313757. Epub 2019 Dec 19. Arterioscler Thromb Vasc Biol. 2020. PMID: 31852223 Free PMC article.