Del Rio CL - Search Results

1

Mavacamten, a precision medicine for hypertrophic cardiomyopathy: From a motor protein to patients.

Nag S, Gollapudi SK, Del Rio CL, Spudich JA, McDowell R. Nag S, et al. Among authors: del rio cl. Sci Adv. 2023 Jul 28;9(30):eabo7622. doi: 10.1126/sciadv.abo7622. Epub 2023 Jul 28. Sci Adv. 2023. PMID: 37506209 Free article. Review.

2

The Impact of Mavacamten on the Pathophysiology of Hypertrophic Cardiomyopathy: A Narrative Review.

Edelberg JM, Sehnert AJ, Mealiffe ME, Del Rio CL, McDowell R. Edelberg JM, et al. Among authors: del rio cl. Am J Cardiovasc Drugs. 2022 Sep;22(5):497-510. doi: 10.1007/s40256-022-00532-x. Epub 2022 Apr 18. Am J Cardiovasc Drugs. 2022. PMID: 35435607 Free PMC article. Review.

3

Myosin in autoinhibited off state(s), stabilized by mavacamten, can be recruited in response to inotropic interventions.

Ma W, Del Rio CL, Qi L, Prodanovic M, Mijailovich S, Zambataro C, Gong H, Shimkunas R, Gollapudi S, Nag S, Irving TC. Ma W, et al. Among authors: del rio cl. Proc Natl Acad Sci U S A. 2024 Feb 20;121(8):e2314914121. doi: 10.1073/pnas.2314914121. Epub 2024 Feb 12. Proc Natl Acad Sci U S A. 2024. PMID: 38346202

4

Acute Effects of Pimobendan on Cardiac Function in Dogs With Tachycardia Induced Dilated Cardiomyopathy: A Randomized, Placebo-Controlled, Crossover Study.

Abbott-Johnson K, Pierce KV, Roof S, Del Rio CL, Hamlin R. Abbott-Johnson K, et al. Among authors: del rio cl. Front Vet Sci. 2021 Jul 1;8:646437. doi: 10.3389/fvets.2021.646437. eCollection 2021. Front Vet Sci. 2021. PMID: 34277749 Free PMC article.

5

Effects of danicamtiv, a novel cardiac myosin activator, in heart failure with reduced ejection fraction: experimental data and clinical results from a phase 2a trial.

Voors AA, Tamby JF, Cleland JG, Koren M, Forgosh LB, Gupta D, Lund LH, Camacho A, Karra R, Swart HP, Pellicori P, Wagner F, Hershberger RE, Prasad N, Anderson R, Anto A, Bell K, Edelberg JM, Fang L, Henze M, Kelly C, Kurio G, Li W, Wells K, Yang C, Teichman SL, Del Rio CL, Solomon SD. Voors AA, et al. Among authors: del rio cl. Eur J Heart Fail. 2020 Sep;22(9):1649-1658. doi: 10.1002/ejhf.1933. Epub 2020 Jul 10. Eur J Heart Fail. 2020. PMID: 32558989 Free PMC article. Clinical Trial.

6

The Super-Relaxed State and Length Dependent Activation in Porcine Myocardium.

Ma W, Henze M, Anderson RL, Gong H, Wong FL, Del Rio CL, Irving T. Ma W, et al. Among authors: del rio cl. Circ Res. 2021 Sep 3;129(6):617-630. doi: 10.1161/CIRCRESAHA.120.318647. Epub 2021 Aug 9. Circ Res. 2021. PMID: 34365814 Free PMC article.

7

The West coast regional safety pharmacology society meeting update: Filling translational gaps in safety assessment.

Abi-Gerges N, McMahon C, Vargas H, Sager P, Chui R, Stevens D, Davila J, Schaub JR, Wu JC, Del Rio C, Mathes C, Miller PE, Burns-Naas LA, Ghetti A. Abi-Gerges N, et al. J Pharmacol Toxicol Methods. 2019 Jul-Aug;98:106582. doi: 10.1016/j.vascn.2019.106582. Epub 2019 May 9. J Pharmacol Toxicol Methods. 2019. PMID: 31077805 Review.

8

Direct Interstitial Decongestion in an Animal Model of Acute-on-Chronic Ischemic Heart Failure.

Abraham WT, Jonas M, Dongaonkar RM, Geist B, Ueyama Y, Render K, Youngblood B, Muir W, Hamlin R, Del Rio CL. Abraham WT, et al. Among authors: del rio cl. JACC Basic Transl Sci. 2021 Nov 22;6(11):872-881. doi: 10.1016/j.jacbts.2021.09.008. eCollection 2021 Nov. JACC Basic Transl Sci. 2021. PMID: 34869951 Free PMC article.

9

Myosin in autoinhibited off state(s), stabilized by mavacamten, can be recruited via inotropic effectors.

Ma W, Del Rio CL, Qi L, Prodanovic M, Mijailovich S, Zambataro C, Gong H, Shimkunas R, Gollapudi S, Nag S, Irving TC. Ma W, et al. Among authors: del rio cl. bioRxiv [Preprint]. 2023 Aug 28:2023.04.10.536292. doi: 10.1101/2023.04.10.536292. bioRxiv. 2023. PMID: 37090664 Free PMC article. Updated. Preprint.

10

Intravenous Infusion of the Novel HNO Donor BMS-986231 Is Associated With Beneficial Inotropic, Lusitropic, and Vasodilatory Properties in 2 Canine Models of Heart Failure.

Hartman JC, Del Rio CL, Reardon JE, Zhang K, Sabbah HN. Hartman JC, et al. Among authors: del rio cl. JACC Basic Transl Sci. 2018 Nov 12;3(5):625-638. doi: 10.1016/j.jacbts.2018.07.003. eCollection 2018 Oct. JACC Basic Transl Sci. 2018. PMID: 30456334 Free PMC article.

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