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A Polygenic Risk Score for Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormalities.
Moll M, Peljto AL, Kim JS, Xu H, Debban CL, Chen X, Menon A, Putman RK, Ghosh AJ, Saferali A, Nishino M, Hatabu H, Hobbs BD, Hecker J, McDermott G, Sparks JA, Wain LV, Allen RJ, Tobin MD, Raby BA, Chun S, Silverman EK, Zamora AC, Ortega VE, Garcia CK, Barr RG, Bleecker ER, Meyers DA, Kaner RJ, Rich SS, Manichaikul A, Rotter JI, Dupuis J, O'Connor GT, Fingerlin TE, Hunninghake GM, Schwartz DA, Cho MH. Moll M, et al. Among authors: hecker j. Am J Respir Crit Care Med. 2023 Oct 1;208(7):791-801. doi: 10.1164/rccm.202212-2257OC. Am J Respir Crit Care Med. 2023. PMID: 37523715
Benchmarking omics-based prediction of asthma development in children.
Wang XW, Wang T, Schaub DP, Chen C, Sun Z, Ke S, Hecker J, Maaser-Hecker A, Zeleznik OA, Zeleznik R, Litonjua AA, DeMeo DL, Lasky-Su J, Silverman EK, Liu YY, Weiss ST. Wang XW, et al. Among authors: hecker j. Respir Res. 2023 Feb 26;24(1):63. doi: 10.1186/s12931-023-02368-8. Respir Res. 2023. PMID: 36842969 Free PMC article.
Fast computation of the eigensystem of genomic similarity matrices.
Hahn G, Lutz SM, Hecker J, Prokopenko D, Cho MH, Silverman EK, Weiss ST, Lange C. Hahn G, et al. Among authors: hecker j. BMC Bioinformatics. 2024 Jan 25;25(1):43. doi: 10.1186/s12859-024-05650-8. BMC Bioinformatics. 2024. PMID: 38273228 Free PMC article.
Gasdermin B, an asthma-susceptibility gene, promotes MAVS-TBK1 signalling and airway inflammation.
Liu T, Liu S, Rui X, Cao Y, Hecker J, Guo F, Zhang Y, Gong L, Zhou Y, Yu Y, Krishnamoorthyni N, Bates S, Chun S, Boyer N, Xu S, Park JA, Perrella MA, Levy BD, Weiss ST, Mou H, Raby BA, Zhou X. Liu T, et al. Among authors: hecker j. Eur Respir J. 2024 May 2;63(5):2301232. doi: 10.1183/13993003.01232-2023. Print 2024 May. Eur Respir J. 2024. PMID: 38514093 Free PMC article.
The Asthma Risk Gene, GSDMB, Promotes Mitochondrial DNA-induced ISGs Expression.
Liu T, Hecker J, Liu S, Rui X, Boyer N, Wang J, Yu Y, Zhang Y, Mou H, Gomez-Escobar LG, Choi AMK, Raby BA, Weiss ST, Zhou X. Liu T, et al. Among authors: hecker j. J Respir Biol Transl Med. 2024 Mar;1(1):10005. doi: 10.35534/jrbtm.2024.10005. Epub 2024 Mar 31. J Respir Biol Transl Med. 2024. PMID: 38737375 Free PMC article.
Polygenic and transcriptional risk scores identify chronic obstructive pulmonary disease subtypes.
Moll M, Hecker J, Platig J, Zhang J, Ghosh AJ, Pratte KA, Wang RS, Hill D, Konigsberg IR, Chiles JW, Hersh CP, Castaldi PJ, Glass K, Dy JG, Sin DD, Tal-Singer R, Mouded M, Rennard SI, Anderson GP, Kinney GL, Bowler RP, Curtis JL, McDonald ML, Silverman EK, Hobbs BD, Cho MH. Moll M, et al. Among authors: hecker j. medRxiv [Preprint]. 2024 May 20:2024.05.20.24307621. doi: 10.1101/2024.05.20.24307621. medRxiv. 2024. PMID: 38826461 Free PMC article. Preprint.
257 results