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Prolonged exposure to lung-derived cytokines is associated with inflammatory activation of microglia in patients with COVID-19.
Grant RA, Poor TA, Sichizya L, Diaz E, Bailey JI, Soni S, Senkow KJ, Pérez-Leonor XG, Abdala-Valencia H, Lu Z, Donnelly HK, Tighe RM, Lomasney JW, Wunderink RG, Singer BD, Misharin AV, Budinger GS. Grant RA, et al. Among authors: singer bd. bioRxiv [Preprint]. 2023 Jul 28:2023.07.28.550765. doi: 10.1101/2023.07.28.550765. bioRxiv. 2023. PMID: 37546860 Free PMC article. Updated. Preprint.
Machine learning links unresolving secondary pneumonia to mortality in patients with severe pneumonia, including COVID-19.
Gao CA, Markov NS, Stoeger T, Pawlowski A, Kang M, Nannapaneni P, Grant RA, Pickens C, Walter JM, Kruser JM, Rasmussen L, Schneider D, Starren J, Donnelly HK, Donayre A, Luo Y, Budinger GRS, Wunderink RG, Misharin AV, Singer BD; NU SCRIPT Study Investigators. Gao CA, et al. Among authors: singer bd. J Clin Invest. 2023 Jun 15;133(12):e170682. doi: 10.1172/JCI170682. J Clin Invest. 2023. PMID: 37104035 Free PMC article.
An Adjudication Protocol for Severe Pneumonia.
Pickens CI, Gao CA, Bodner J, Walter JM, Kruser JM, Donnelly HK, Donayre A, Clepp K, Borkowski N, Wunderink RG, Singer BD; NU SCRIPT Study Investigators. Pickens CI, et al. Among authors: singer bd. Open Forum Infect Dis. 2023 Jul 1;10(7):ofad336. doi: 10.1093/ofid/ofad336. eCollection 2023 Jul. Open Forum Infect Dis. 2023. PMID: 37520413 Free PMC article.
Novel subtypes of severe COVID-19 respiratory failure based on biological heterogeneity: a secondary analysis of a randomized controlled trial.
Alipanah-Lechner N, Hurst-Hopf J, Delucchi K, Swigart L, Willmore A, LaCombe B, Dewar R, Lane HC, Lallemand P, Liu KD, Esserman L, Matthay MA, Calfee CS; I-SPY COVID Consortium. Alipanah-Lechner N, et al. Crit Care. 2024 Feb 21;28(1):56. doi: 10.1186/s13054-024-04819-0. Crit Care. 2024. PMID: 38383504 Free PMC article. Clinical Trial.
Mitochondria regulate proliferation in adult cardiac myocytes.
Waypa GB, Smith KA, Mungai PT, Dudley VJ, Helmin KA, Singer BD, Peek CB, Bass J, Beussink-Nelson L, Shah SJ, Ofman G, Wasserstrom JA, Muller WA, Misharin AV, Budinger GRS, Abdala-Valencia H, Chandel NS, Dokic D, Bartom ET, Zhang S, Tatekoshi Y, Mahmoodzadeh A, Ardehali H, Thorp EB, Schumacker PT. Waypa GB, et al. Among authors: singer bd. J Clin Invest. 2024 May 9:e165482. doi: 10.1172/JCI165482. Online ahead of print. J Clin Invest. 2024. PMID: 38722697 Free article.
Temporal correlation between postreperfusion complement deposition and severe primary graft dysfunction in lung allografts.
Cerier E, Kurihara C, Kaiho T, Toyoda T, Manerikar A, Kandula V, Thomae B, Yagi Y, Yeldandi A, Kim S, Avella-Patino D, Pandolfino J, Perlman H, Singer B, Scott Budinger GR, Lung K, Alexiev B, Bharat A. Cerier E, et al. Am J Transplant. 2024 Apr;24(4):577-590. doi: 10.1016/j.ajt.2023.11.006. Epub 2023 Nov 15. Am J Transplant. 2024. PMID: 37977230
Prolonged exposure to lung-derived cytokines is associated with activation of microglia in patients with COVID-19.
Grant RA, Poor TA, Sichizya L, Diaz E, Bailey JI, Soni S, Senkow KJ, Pérez-Leonor XG, Abdala-Valencia H, Lu Z, Donnelly HK, Simons LM, Ozer EA, Tighe RM, Lomasney JW, Wunderink RG, Singer BD, Misharin AV, Budinger GRS; Northwestern University Successful Clinical Response In Pneumonia Therapy (NU SCRIPT) Investigators. Grant RA, et al. Among authors: singer bd. JCI Insight. 2024 Mar 19;9(8):e178859. doi: 10.1172/jci.insight.178859. JCI Insight. 2024. PMID: 38502186 Free article.
109 results