Koenig SG - Search Results

1

Characterization of antisense oligonucleotide and guide ribonucleic acid diastereomers by hydrophilic interaction liquid chromatography coupled to mass spectrometry.

Goyon A, Blevins MS, Napolitano JG, Nguyen D, Goel M, Scott B, Wang J, Koenig SG, Chen T, Zhang K. Goyon A, et al. Among authors: koenig sg. J Chromatogr A. 2023 Oct 11;1708:464327. doi: 10.1016/j.chroma.2023.464327. Epub 2023 Aug 25. J Chromatogr A. 2023. PMID: 37660562

2

Automated high-throughput preparation and characterization of oligonucleotide-loaded lipid nanoparticles.

Fan Y, Yen CW, Lin HC, Hou W, Estevez A, Sarode A, Goyon A, Bian J, Lin J, Koenig SG, Leung D, Nagapudi K, Zhang K. Fan Y, et al. Among authors: koenig sg. Int J Pharm. 2021 Apr 15;599:120392. doi: 10.1016/j.ijpharm.2021.120392. Epub 2021 Feb 25. Int J Pharm. 2021. PMID: 33639228

3

Predictive high-throughput screening of PEGylated lipids in oligonucleotide-loaded lipid nanoparticles for neuronal gene silencing.

Sarode A, Fan Y, Byrnes AE, Hammel M, Hura GL, Fu Y, Kou P, Hu C, Hinz FI, Roberts J, Koenig SG, Nagapudi K, Hoogenraad CC, Chen T, Leung D, Yen CW. Sarode A, et al. Among authors: koenig sg. Nanoscale Adv. 2022 Feb 4;4(9):2107-2123. doi: 10.1039/d1na00712b. eCollection 2022 May 3. Nanoscale Adv. 2022. PMID: 36133441 Free PMC article.

4

Process Robustness in Lipid Nanoparticle Production: A Comparison of Microfluidic and Turbulent Jet Mixing.

O'Brien Laramy MN, Costa AP, Cebrero YM, Joseph J, Sarode A, Zang N, Kim LJ, Hofmann K, Wang S, Goyon A, Koenig SG, Hammel M, Hura GL. O'Brien Laramy MN, et al. Among authors: koenig sg. Mol Pharm. 2023 Aug 7;20(8):4285-4296. doi: 10.1021/acs.molpharmaceut.3c00390. Epub 2023 Jul 18. Mol Pharm. 2023. PMID: 37462906

5

Challenges in the structure determination of a dimeric impurity found during development of GDC-0326.

Segraves NL, Koenig SG, Stults J, Ma S, DiPasquale AG, Robinson SJ, Russell DJ. Segraves NL, et al. Among authors: koenig sg. J Pharm Biomed Anal. 2022 May 10;213:114627. doi: 10.1016/j.jpba.2022.114627. Epub 2022 Jan 29. J Pharm Biomed Anal. 2022. PMID: 35276506

6

The "η-sweet-spot" (η_max) in liquid-assisted mechanochemistry: polymorph control and the role of a liquid additive as either a catalyst or an inhibitor in resonant acoustic mixing (RAM).

Gonnet L, Borchers TH, Lennox CB, Vainauskas J, Teoh Y, Titi HM, Barrett CJ, Koenig SG, Nagapudi K, Friščić T. Gonnet L, et al. Among authors: koenig sg. Faraday Discuss. 2023 Jan 5;241(0):128-149. doi: 10.1039/d2fd00131d. Faraday Discuss. 2023. PMID: 36239309

7

Direct mechanocatalysis by resonant acoustic mixing (RAM).

Lennox CB, Borchers TH, Gonnet L, Barrett CJ, Koenig SG, Nagapudi K, Friščić T. Lennox CB, et al. Among authors: koenig sg. Chem Sci. 2023 May 18;14(27):7475-7481. doi: 10.1039/d3sc01591b. eCollection 2023 Jul 12. Chem Sci. 2023. PMID: 37449073 Free PMC article.

8

Introduction of a process mass intensity metric for biologics.

Budzinski K, Blewis M, Dahlin P, D'Aquila D, Esparza J, Gavin J, Ho SV, Hutchens C, Kahn D, Koenig SG, Kottmeier R, Millard J, Snyder M, Stanard B, Sun L. Budzinski K, et al. Among authors: koenig sg. N Biotechnol. 2019 Mar 25;49:37-42. doi: 10.1016/j.nbt.2018.07.005. Epub 2018 Aug 16. N Biotechnol. 2019. PMID: 30121383

9

Metal-Catalyzed Organic Reactions by Resonant Acoustic Mixing.

Gonnet L, Lennox CB, Do JL, Malvestiti I, Koenig SG, Nagapudi K, Friščić T. Gonnet L, et al. Among authors: koenig sg. Angew Chem Int Ed Engl. 2022 Mar 21;61(13):e202115030. doi: 10.1002/anie.202115030. Epub 2022 Feb 9. Angew Chem Int Ed Engl. 2022. PMID: 35138018

10

Three-Component Coupling of Arenes, Ethylene, and Alkynes Catalyzed by a Cationic Bis(phosphine) Cobalt Complex: Intercepting Metallacyclopentenes for C-H Functionalization.

Whitehurst WG, Kim J, Koenig SG, Chirik PJ. Whitehurst WG, et al. Among authors: koenig sg. J Am Chem Soc. 2022 Mar 16;144(10):4530-4540. doi: 10.1021/jacs.1c12646. Epub 2022 Mar 4. J Am Chem Soc. 2022. PMID: 35245039 Free PMC article.

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